Zhongguo Yi Xue Ke Xue Yuan Xue Bao
December 2019
To evaluate the NoSAS score and the obstructive sleep apnea hypopnea syndrome(OSAHS)screening model for female snorers with obstructive sleep apnea(OSA)in females and compare the performance of these two tools. A total of 425 females with suspected OSA who underwent overnight polysomnography(PSG)were consecutively recruited into this study.The above two questionnaires were completed.
View Article and Find Full Text PDFTo compare the performance of contrast-enhanced ultrasound (CEUS) using high-frequency linear and convex probes in the detection of small colorectal liver metastases (CRLMs). A total of 85 patients with 143 small CRLMs were evaluated. High-frequency ultrasound (US) and CEUS detected significantly more superficial lesions within 60 mm below the skin than a convex probe (p <0.
View Article and Find Full Text PDFAim: To study the effects of ginsenoside-Ro on cell proliferation and cytokine production in murine splenocytes.
Methods: The effect of ginsenoside-Ro on murine splenocytes proliferation was studied using [3H] thymidine incorporation assay. Effects of ginsenoside-Ro on the production of cytokines interleukin-2 (IL-2), interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) from murine splenocytes were detected by ELISA method.
Seven protopanaxatriol-type ginsenosides and their aglycones including PPT, PT, -Re, -Rg (1), -F (1), -Rh (1), 20(R)-Rh (1) which are closely related in structure were studied for their effects on type 1 and type 2 cytokines production from murine splenocytes and their related mechanisms were examined. The results indicate that PPT, PT and ginsenoside-Re show hardly any or weak effects on concanavalin A (Con A)-induced production of IFN-gamma and IL-4. Ginsenoside-Rh (1) and 20(R)-Rh (1) induce a Con A-induced type 1 cytokine pattern by increasing the production of interleukin-12 (IL-12), the expression of IFN-gamma, T-bet and enhancing NF-kappaB DNA binding activity.
View Article and Find Full Text PDFActa Pharmacol Sin
December 2004
Aim: To investigate the immunoenhancing activity of ginsenoside-F3 in murine spleen cells and explore its mechanism.
Methods: The enhancing effect of ginsenoside-F3 on murine spleen cell proliferation was studied using [3H]thymidine incorporation assay. Effects of ginsenoside-F3 on the production of type 1 cytokines IL-2, IFN-gamma, and type 2 cytokines IL-4 and IL-10 from murine spleen cells were detected by ELISA method.