[Study of mechanism of differentiation of bone stromal stem cells into neurons in vitro].

Aim: To explore the mechanism of differentiation of bone marrow stromal cells (BMSCs) into neurons in different micro-environments in vitro.

Methods: BMSCs were isolated from bone marrow of SD rats and cultured and expanded in vitro. After being identified by immunofluorescence staining, the BMSCs labeled with PKH67 were co-cultured with foetal brain neural cells in the same plate well or in two-layer Petri dish.