Publications by authors named "Jun-Yang Liang"
Article Synopsis
- A case-control study in China investigates the connection between Toxoplasma gondii infection and rheumatic diseases, revealing higher infection rates in rheumatic patients compared to controls (17.25% vs. 10.70%).
- The study found no significant differences in T. gondii seroprevalence among different types of rheumatic conditions, nor was disease duration linked to infection rates.
- Three risk factors associated with higher T. gondii seroprevalence were identified: having cats at home, a history of blood transfusions, and consuming raw shellfish, highlighting the need for increased awareness in rheumatic patient care.
The efficacy and potential mechanism of cnidium lactone to inhibit osteoclast differentiation.
Artif Cells Nanomed Biotechnol
December 2019
Cnidium lactone is effective in the maintenance of bone mass in various osteoporosis models; however, the precise molecular mechanisms are not understood. In this study, we investigated the effects and underlying mechanisms of action of cnidium lactone on receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis. Cnidium lactone dose-dependently inhibited osteoclast differentiation and formation, decreased the bone-resorbing activity of osteoclasts, and downregulated the expression of osteoclast differentiation marker genes.
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