Publications by authors named "Jun-Yan Song"
Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery.
Clin Cosmet Investig Dermatol
November 2023
Purpose: Psoriasis is a chronic, multi-system skin disease that can be influenced by immunological, environmental, and genetic factors. Plasma metabolomic analysis can provide a great deal of information on potential diagnostic biomarkers, pathogenesis and personalized treatment. However, the role of metabolites in psoriasis is unknown.
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- Four fluorescent molecules based on triphenylamine or carbazole and benzothiadiazole were successfully created and studied for their properties.
- These molecules are classified as donor-acceptor (D-A) luminogens and displayed varying solid-state fluorescence behaviors.
- All four compounds demonstrated notable reversible mechanochromism, meaning their fluorescence intensity changed significantly with mechanical stress.