Publications by authors named "Jun-Tian Huang"
Article Synopsis
- * A case study of a 24-year-old woman revealed a new mutation in the CARD9 gene linked to her CNS candidiasis, despite her being previously immunocompetent.
- * The research highlighted how this mutation affects immune responses, showing decreased inflammatory cytokines, poor Th17 cell differentiation, and reduced neutrophil presence in the CNS, suggesting genetic testing for CARD9 mutations in similar cases.
Objectives: To explore the seroprevalence of anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibodies in non-HIV cryptococcal meningitis (CM) and assess its predictive value for survival.
Methods: This is a retrospective study of 12 years of non-HIV CM. We detected serum anti-GM-CSF autoantibodies, and evaluated the clinical features and outcomes, together with the exploration of prognostic factors for 2-week and 1-year survival.
Chronic pulmonary aspergillosis (CPA) is a chronic and progressive fungal disease with high morbidity and mortality. Avoiding diagnostic delay and misdiagnosis are concerns for CPA patients. However, diagnostic practice is poorly evaluated, especially in resource-constrained areas where Aspergillus antibody testing tools are lacking.
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