One new phenolic glycoside () and one new benzofuran derivative () were isolated from the leaves of The structures of these compounds were established by using comprehensive spectroscopic data analysis, including the 1D and 2D NMR, IR, HR-ESI-MS, electronic circular dichroism and comparison with literature data. All isolates were evaluated for the inhibition against the production of NO by LPS-stimulated RAW 264.7 macrophages.
View Article and Find Full Text PDFFour previously unreported sesquiterpenoid diasteromers, arteannoides U-X (1-4), together with one new norsesquiterpenoid 5 (arteannoide Y) and one undescribed rearranged cadinene sesquiterpenoid 6 (arteannoide Z) were obtained from the dried aerial parts of Artemisia annua (Qinghao). Notably, arteannoides U-X (1-4) are four stereoisomers that possess the same molecules and the same planar connectivity, but differ from each other in configuration at a certain stereocenter. Their accurate structures were unambiguously identified and distinguished by extensive spectroscopic analyses, NMR calculations with DP4+ analysis, electronic circular dichroism (ECD) calculations and X-ray diffraction analyses.
View Article and Find Full Text PDFA new phenylpropanoid allopyranoside () and a new indolinone alkaloid () were isolated from the rhizomes of (syn. ). The structures of those two compounds were deduced as cimicifugaside F () and 3,11-(3-methyl-2-butenylidene acid)-2-indolinone-1---d-glucopyranoside () by detailed analysis of their MS, 1D and 2D NMR data and comparison with literatures.
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