Publications by authors named "Jun-Qin Liang"
Background: The single nucleotide polymorphism (SNP) rs2476601 of the protein tyrosine phosphatase, nonreceptor type 22 (PTPN22) gene has been presented to implicate in the pathogenesis of alopecia areata (AA) in a few association investigations with limited sample size and inconsistent conclusions.
Methods: The aim of the current meta-analysis was to assess and synthesize the presently available data on the connection between rs2476601 and AA vulnerability. Six electronic databases, including EMBASE, PubMed, Web of Science, the Cochrane Library, Wanfang data, and the China National Knowledge Infrastructure database (CNKI), were systematically retrieved for relevant observational studies published previous to November 2018.
Background: gene plays an important role in melanoma, although the specific mechanism involved is unclear. The aim of this study was to screen and identify the relative miRNAs with the regulation of hTERT in melanoma.
Materials And Methods: Quantitative real-time polymerase chain reaction (q-PCR) and immunohistochemistry were performed to detect hTERT mRNA and protein expression in 36 formalin-fixed paraffin-embedded melanoma tissues and 36 age- and sex-matched pigmented nevi cases, respectively.
Article Synopsis
- Kaposi sarcoma (KS) is a common tumor in HIV patients, with ongoing debate about whether it's a true neoplasm or simply a hyperplastic growth.
- Research involved DNA analysis from KS lesions and hemangiomas, using specific techniques to assess the clonality of KS.
- Results indicated that KS has a monoclonal origin, supporting the idea that it is a neoplastic disease rather than a benign condition.