Publications by authors named "Jun-Qi Si"
[Effect of Acute Myeloid Leukemia Cells on the Proliferation and Apoptosis of Bone Marrow-Derived Mesenchymal Stromal Cells].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2022
Article Synopsis
- The study aimed to understand how acute myeloid leukemia (AML) cells affect the growth and survival of bone marrow-derived mesenchymal stromal cells (BM-MSC).
- Researchers used murine models of AML overexpressing MLL-AF9 to compare BM-MSC from wild type and AML mice, employing techniques like flow cytometry and fluorescence microscopy.
- Results showed that BM-MSC from AML mice had an increased number and proliferation rate, with a reduced rate of apoptosis, indicating that AML cells enhance BM-MSC growth and survival.