Publications by authors named "Jun-Peng You"
Front Immunol
November 2022
Article Synopsis
- Systemic lupus erythematosus (SLE) is an autoimmune disease linked to the production of autoantibodies, and the role of long non-coding RNAs (lncRNAs) in its development is still not fully understood.
- * The study utilized genetic association analysis from existing genome-wide association studies (GWAS) and validated findings with an independent cohort, identifying 33 single nucleotide polymorphisms (SNPs) associated with SLE susceptibility.
- * The most significant SNP, rs844649, showed a strong correlation with SLE and increased mRNA and protein expression levels in blood samples from patients, suggesting that lncRNA coding genes play a crucial role in the disease's susceptibility.*
