Publications by authors named "Jun-Ning Zhang"
[Analysis of genetic diagnosis results of 1 501 suspected Cases of thalassemia patients from 2020 to 2022].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2024
Article Synopsis
- The study investigates the prevalence and genotypes of thalassemia in Lingui District, Guilin City, helping to inform prevention strategies.
- A retrospective analysis of 1,501 suspected cases revealed a 45.17% carrier rate, with 379 α-thalassemia and 270 β-thalassemia cases identified.
- The findings highlight the complexity of thalassemia genotypes in the region, underscoring the need for genetic counseling and prenatal testing efforts.
Aim: Little is known about the relationship between XRCC1 Codon399 polymorphisms and radiotherapy (RT) outcomes in patients with nasopharyngeal carcinoma (NPC). We aimed to investigate whether XRCC1 Codon399 polymorphisms were correlated to treatment efficacy and normal tissue toxicity in Chinese patients with locally advanced NPC after RT.
Methods: Sixty eligible patients with NPC stage III-IVa were recruited.
Background And Objective: Recently, the theory of cancer stem cells (CSCs) has presented new targets and orientations for tumor therapy. The major difficulties in researching CSCs include their isolation and purification. The aim of this study is to identify and characterize the side population (SP) cells in small cell lung cancer (SCLC) cell line H446, which lays the foundation for the isolation and purification of CSCs.
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