Publications by authors named "Jun-Miao Xu"
Article Synopsis
- The research investigates the role of histone deacetylase 10 (HDAC10) in the adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and its implications for steroid-induced avascular necrosis of the femoral head (SANFH).
- Dexamethasone treatment was found to worsen the differentiation balance of BMSCs, with HDAC10 showing significantly reduced expression in adipogenic differentiation models.
- The study suggests that decreased HDAC10 levels lead to increased PPARγ expression, contributing to the progression of SANFH, and highlights potential therapeutic avenues for the condition.
Due to persistent inflammation and oxidative stress reactions, achieving drug absorption in diabetic wounds is challenging. To overcome this problem, our article presents a composite hydrogel, GelMA-GA/DMOG@GDNP, which consists of gelatin methacryloyl (GelMA) treated with gallic acid (GA) and encapsulating ginseng-derived nanoparticles (GDNPs) loaded with dimethyloxallyl glycine (DMOG). The composite hydrogel demonstrates excellent biocompatibility.
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