Publications by authors named "Jun-Jun Zhao"

Background: To assess the impact of coronavirus disease-2019 (COVID-19) in its outbreak stage (Spring Festival in 2020) on oral emergency services.

Methods: Oral emergency cases in Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, during the Spring Festival after the outbreak of the COVID-19 epidemic in 2020 were collected and compared with those in 2018 and 2019. Electronic medical records including the visited department, age, sex, time, date, region, and diagnosis were collected and analyzed.

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Corona virus disease 2019 (COVID-19) has become a Public Health Emergency of International Concern since its outbreak, and whether COVID-19 can transmit by aerosol remains controversial. The problem of bio-aerosol transmission in the relatively confined dental clinics has aroused wide attention in the field of dentistry. This review provided a most updated summary on the relation between bio-aerosols and dental clinics, which included the microorganisms in bio-aerosols, the bio-aerosol transmission and the sources testing methods, temporal and spatial distribution of dental bio-aerosols and summarized how to reduce the exposure to bio-aerosols in dental clinics.

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Purpose: To evaluate the outcome of coronectomy for management of impacted mandibular third molars in close proximity to inferior alveolar nerve (IAN).

Methods: Ten patients with impacted mandibular third molars which approached or was close to the inferior alveolar nerve diagnosed on panoramic film and cone-beam CT (CBCT) scan were included in the study. Coronectomy was conducted at the cemento-enamel junction, leaving the roots below the alveolar crest and primary closure was performed.

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Purpose: This study aimed to evaluate the possible antagonistic effects of Lactobacillus acidophilus on Porphyromonas gingivalis, and detect inhibition of Lactobacillus acidophilus on Porphyromonas gingivalis when they are co-cultured with human gingival epithelial cells.

Materials And Methods: Human gingival epithelial cells were co-cultured with Lactobacillus acidophilus and Porphyromonas gingivalis alone or together. The amount of Porphyromonas gingivalis adhering to or invading the epithelial cells were determined by bacterial counts.

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Purpose: To evaluate the effect of Mtwo NiTi files in the management of calcified root canals.

Methods: Thirty-five calcified root canals from 21 cases unsuccessfully prepared with C-Pilot files and EDTA were treated with Mtwo NiTi files and EDTA. The data was analyzed with SAS 9.

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Lymphoepithelioma-like gastric carcinoma is a rare type of gastric cancer characterized by a carcinoma with intense stromal lymphocytic infiltration. Although lymphocytic infiltration is closely associated with Epstein-Barr virus (EBV) infection, concomitant occurrence with differentiated adenocarcinoma is relatively rare. The clinical manifestations of lymphoepithelioma-like gastric carcinoma (including EBV-positive and -negative forms) are similar to those of gastric cancer, and the diagnosis is based on pathologic, histologic, and immunohistochemical findings.

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Introduction: In previous studies, we found that hypoxia promoted the mineralization of dental pulp cells (DPCs). However, the clinical application of hypoxia as a therapy is questionable or unfeasible. Deferoxamine (DFO), a medication for iron overload, has also been shown to induce hypoxia.

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Porphyromonas gingivalis alters cytokine expression in gingival epithelial cells, stimulating inflammatory responses that may lead to periodontal disease. This study explored the effect of Lactobacillus acidophilus on the specific expressions of the interleukins (ILs) IL1B, IL6, and IL8 induced by the pathogen. Human gingival epithelial cells were co-cultured with P.

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Purpose: To evaluate the possible antagonistic effects of Lactobacillus acidophilus (La) and Bifidobacterium adolescents (Ba) on Porphyromonas gingivalis (Pg) and Fusobacteriurn nuclearum (Fn).

Methods: Cylinder plate method was used to observe the inhibition zone formation.The suspensions of periodontal pathogens were mixed with cell free solutions of probiotics respectively, to investigate the antagonistic effect on the production of probiotics.

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Objective: To study the clinicopathological features of primary splenic histiocytic sarcoma.

Methods: Clinicopathological characterstics were analyzed in a case of primary splenic histiocytic sarcoma and related literatures were reviewed.

Results: A 69-year old woman had unexplained debility and palpitation after exertion for a month.

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In the crystal structure of the title salt, (C(7)H(7)N(2)S)(2)[Co(C(8)H(8)O(5))(2)]·6H(2)O, the heterocyclic N atom of the 2-amino-benzothia-zole mol-ecule is protonated. The Co(II) atom is situated on an inversion centre and exhibits a slightly distorted octa-hedral CoO(6) coordination defined by the bridging O atoms of the bicyclo-heptane unit and four carboxyl-ate O atoms of two symmetry-related and fully deprotonated ligands. The crystal packing is stabilized by N-H⋯O hydrogen bonds between the cations and anions and by O-H⋯O hydrogen bonds including the crystal water mol-ecules.

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Objective: To study the expression of COX-2 and pregnancy associate plasma protein A (PAPP-A) in coronary arteries and their relationship with acute coronary syndrome.

Methods: Twenty-one autopsy cases with acute coronary syndrome encountered during the period from 2002 to 2007 were enrolled into the study. Another 21 autopsy cases without evidence of acute coronary syndrome were used as the controls.

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Purpose: To analyze the effect of topical anesthetics in taking dental X-ray film.

Methods: 300 patients, who needed to take dental X-ray photography of maxillary or mandibular molar were randomly assigned to 3 groups. Bisecting angle technique was used to take the film.

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Purpose: To evaluate the pharmacologic effect of garlic on oral bacteriostasis and root detoxification.

Methods: Eight representative oral anaerobes (58 strains) including Streptococcus (9), Peptococcus (4), Lactobacillus (6), Actinomyces (3), Veillonella (10), Porphyromonas (12), Prevatella (3), Fusobacterium (11) to garlic juice were systematically studied by classical tube susceptibility test. The periodontally involved roots (12) were selected and the slices (6 mm x 3 mm x 1 mm) were prepared on the exposed root surface.

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Purpose: To compare the effect of chloromycetin and normal saline on proliferation and ultrastructure of cultured periodontal ligament cells.

Methods: Human periodontal ligament cells were exposed for 1 hour to 0.25% chloromycetin, normal saline and DMEM culture medium.

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Aim: To study the pharmaceutical characterization, the pharmacokinetics and relative bioavailability of glimepiride gel-matrix controlled-release patch in rats.

Methods: An HPLC method was established for the determination of glimepiride in the permeation receptor and patch. The permeation rate and penetration mechanism of glimepiride-TDDS through rabbit skin in vitro was examined.

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The present study evaluated for the first time the dose-effectiveness, therapeutic time-window and long-term efficacy of the neuroprotection of catalpol by behavioral and histological measures in gerbils subjected to transient global cerebral ischemia. Catalpol (1 mg/kg ip) used immediately after reperfusion and repeatedly at 12, 24, 48 and 72 h significantly rescued neurons in the hippocampal CA1 subfield and reduced cognitive impairment. The neuroprotective efficacy of catalpol became more evident at the doses of 5 and 10 mg/kg.

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Objective: 9548 middle school students from 11-19 age at Huangpu District in Shanghai were investigated to study the prevalence of juvenile periodontitis(JP). The purpose of the present study was to discover JP at early stage and make correct diagnosis, so the patients can be treated on time.

Methods: From January 2001 to April 2001, debris index(DI), calculus index(CI), sulcus bleeding index(SBI) and community periodontal index for treatment needs (CPITN) were examined in each student.

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Objective: In order to search the cause of dental caries and periodontitis.

Methods: Selected 70 patients with severe chronic periodontitis (CP group) and 50 patients with caries sensitivity (CS group) in clinical adults of oral medicine (18 to 50-year-old) during 1 year. Parameters of oral hygiene, caries and periodontitis were recorded in the typical groups of CP and CS.

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