Identification of novel variations in the NTRK1 gene causing congenital insensitivity to pain with anhidrosis.

Background: Congenital insensitivity to pain (CIP) conditions are a group of Mendelian disorders with clinical and genetic heterogeneity. CIP with anhidrosis (CIPA) is a distinct subtype caused by biallelic variants in the NTRK1 gene.

Methods: In this study, six families with CIPA were recruited and submitted to a series of clinical and genetic examinations.

Compact Feeding Network for Array Radiations of Spoof Surface Plasmon Polaritons.

We propose a splitter feeding network for array radiations of spoof surface plasmon polaritons (SPPs), which are guided by ultrathin corrugated metallic strips. Based on the coupled mode theory, SPP fields along a single waveguide in a certain frequency range can be readily coupled into two adjacent branch waveguides with the same propagation constants. We propose to load U-shaped particles anti-symmetrically at the ends of such two branch waveguides, showing a high integration degree of the feeding network.

[Effects of seasonal snow cover on soil nitrogen transformation in alpine ecosystem: a review].

Seasonal snow cover has pronounced effects on the soil nitrogen concentration and transformation in alpine ecosystem. Snowfall is an important form of nitrogen deposition, which directly affects the content of soil available nitrogen. Different depths and different duration of snow cover caused by snowfall may lead the heterogeneity of abiotic factors (soil temperature and moisture) and biotic factors (soil microbes, alpine plants, and alpine animals), and further, produce complicated effects on the mineralization and immobilization of soil nitrogen.

Supernatant of bone marrow mesenchymal stromal cells induces peripheral blood mononuclear cells possessing mesenchymal features.

Increasing evidence shows that some cells from peripheral blood fibroblast-like mononuclear cells have the capacity to differentiate into mesenchymal lineages. However, the insufficiency of these cells in the circulation challenges the cell isolation and subsequently limits the clinical application of these cells. In the present study, the peripheral blood mononuclear cells (pbMNCs) were isolated from wound animals and treated with the supernatant of bone marrow mesenchymal stromal cells (bmMSCs).