Long noncoding RNA CDKN2B-AS1 interacts with transcription factor BCL11A to regulate progression of cerebral infarction through mediating MAP4K1 transcription.

The effective therapeutic approach of cerebral infarction is limited because of its underlying complexity. Recently, multiple long noncoding RNAs (lncRNAs) have been identified in the pathogenesis of cerebral infarction. Here, the current study aims to explore the interaction among lncRNA cyclin-dependent kinase inhibitor-2B-antisense RNA 1 (CDKN2B-AS1), transcription factor B-cell lymphoma/leukemia 11A (BCL11A), and MAPKK kinase kinase 1 (MAP4K1) and further investigate whether they affect cerebral infarction progression.

[Response of grain-filling properties and quality of winter wheat to drip irrigation in Xinjiang, China].

To provide theoretical basis for the water-saving, high-yield and good quality cultivation techniques of drip-irrigated winter wheat, the wheat cultivar 'Xindong 22' was adopted as the test material, and five irrigation amounts including 3150 (W), 3900 (W), 4650 (W), 5400 (W) and 0 (CK) m·hm were adopted to investigate effects of drip irrigation amount on grain filling dynamics and quality traits in 2012-2013 and 2013-2014 wheat growing seasons in Xinjiang. Results indicated that the grain-filling dynamics of drip-irrigated winter wheat in different treatments presented the "S" shape curve, and accorded with the Logistic model with high fitting degree. The fast increase period of wheat grain-filling was measured at 12-20 days after anthesis.