Publications by authors named "Jun-Jiao Hu"

Background: The focus of neuro-oncology research has changed from histopathologic grading to molecular characteristics, and medical imaging routinely follows this change.

Purpose: To compare the diagnostic performance of amide proton transfer (APT) and four diffusion models in gliomas grading and isocitrate dehydrogenase (IDH) genotype.

Study Type: Prospective.

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Background: At present, there remains a lack of a reliable indicator for monitoring renal function in patients with hyperuricemia.

Purpose: This study aimed to evaluate the feasibility of diffusion kurtosis imaging in the assessment of renal function in patients with hyperuricemia.

Material And Methods: A total of 75 male participants, including 25 with asymptomatic hyperuricemia, 25 with gouty arthritis, and 25 age-matched male healthy controls, were enrolled in this study.

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Article Synopsis
  • The study aimed to determine whether early diabetic nephropathy (DN) in patients with diabetes could be detected using advanced MRI techniques like blood oxygenation level dependent (BOLD) imaging and diffusion tensor imaging (DTI).
  • 30 diabetic patients were divided into two groups based on their albumin levels, alongside 15 healthy control subjects, with comprehensive urine and blood tests performed prior to imaging.
  • The research found significant differences in imaging parameters (ADC, FA, and R2* values) across the groups, indicating that these MRI techniques could effectively identify early DN in diabetic patients.
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Background: Hyperuricemia is an independent risk factor for onset and progression of kidney disease. However, there remains a lack of a reliable and noninvasive biomarker to identify and monitor the changes of renal function in patients with hyperuricemia.

Purpose: To assess the utility of intravoxel incoherent motion (IVIM) parameters in identifying the early changes of renal function in patients with hyperuricemia.

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