Publications by Jun-Ichiro Kan

Publications by authors named "Jun-Ichiro Kan"

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Interleukin-17A expression in human synovial mast cells in rheumatoid arthritis and osteoarthritis.

Jun-Ichiro Kan Shintaro Mishima Jun-Ichi Kashiwakura Tomomi Sasaki-Sakamoto Masayuki Seki

Allergol Int

September 2016

Background: Interleukin (IL)-17A plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). The expression of IL-17A in synovial mast cells (MCs) in RA and osteoarthritis (OA) has been reported, but the frequencies of IL-17A expression in synovial MCs have varied. The aim of this study was to investigate whether IL-17A expression is upregulated in human synovial MCs in RA and to elucidate the mechanism of IL-17A expression in synovial MCs.

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