Publications by authors named "Jun-Ichiro Gyotoku"
Article Synopsis
- Fluid flow significantly influences bone cells, and recent studies indicate that primary cilia and ion channels are involved in how kidney cells detect flow.
- Researchers examined whether kidney and bone cells have similar mechanisms for detecting fluid flow, focusing on osteoblastic cells (MC3T3-E1) and using fluorescence staining to observe primary cilia.
- The findings revealed that these bone cells respond to both fluid flow and changes in temperature, suggesting a shared mechanism for flow detection between kidney and bone cells.
Cell culture flasks applicable for altered gravity conditions, such as centrifugation, clino-rotation or microgravity in space, were manufactured for trial. The flask has flat polystyrene surface for monolayer culture and gas-permeable film window on the opposite face. The space in-between consists the culture chamber to be filled with liquid medium.
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