Publications by authors named "Jun-Guo Zhang"
Objective: With the increased population mobility and the transition in population policy, scholars are quite concerned about family planning/sexual and reproductive health (SRH) and related factors among internal migrant population of reproductive age. Therefore, the proposed study was designed to explore the association between factors related to family planning/SRH and contraceptive use as well as consistent condom use among the above-described population in China.
Design: Cross-sectional study.
Article Synopsis
- The study analyzes the statistical performance of various burden tests (like CMC, WST, SUM) in genetic association studies focused on rare variants using simulated datasets.
- Results indicate that the type I error rate for all tests is close to 0.05, and the power of these methods varies based on factors like linkage disequilibrium (LD) and the effect direction of the variants.
- It concludes that factors such as sample size, effect direction, and the presence of non-associated variants significantly influence the effectiveness of these burden tests, highlighting the importance of integrating prior biological information when selecting methods.
[Non-parametric Bootstrap estimation on the intraclass correlation coefficient generated from quantitative hierarchical data].
Zhonghua Liu Xing Bing Xue Za Zhi
September 2013
This paper aims to achieve Bootstraping in hierarchical data and to provide a method for the estimation on confidence interval(CI) of intraclass correlation coefficient(ICC).First, we utilize the mixed-effects model to estimate data from ICC of repeated measurement and from the two-stage sampling. Then, we use Bootstrap method to estimate CI from related ICCs.
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Premise Of The Study: Polymorphic microsatellite primers were developed in the seagrass Halophila ovalis to investigate genetic variation. •
Methods And Results: Ten polymorphic microsatellite loci were developed in Halophila ovalis. The number of alleles per locus ranged from 2 to 12 across 80 H.
The FPS1 gene coding for the Fps1p aquaglyceroporin protein of an industrial strain of Saccharomyces cerevisiae was disrupted by inserting CUP1 gene. Wild-type strain, CE25, could only grow on YPD medium containing less than 0.45% (v/v) acetic acid, while recombinant strain T12 with FPS1 disruption could grow on YPD medium with 0.
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