Therapeutic effect of folic acid combined with decitabine on diabetic mice.

Aim: To evaluate the therapeutic effect of folic acid combined with decitabine on diabetic mice.

Methods: The diabetic model of mice were randomly divided into model group, folic acid group, decitabine group, folic acid combined with decitabine group, and C57 mice as normal control group. The density of retinal blood vessels and retinal thickness were detected by fundus photography and optical coherence tomography, respectively.

Survey of the Prosthogonimus spp. metacercariae infection in the second intermediate host dragonfly in Heilongjiang Province, China.

Prosthogonimiasis poses a threat to the reproductive system of poultry and wild birds, which are the definitive hosts of the parasite causing this disease. However, the parasite infection of the second intermediate host (dragonfly), the primary vector of this pathogen, is rarely reported. In this study, the prevalence of Prosthogonimus infection in dragonflies was investigated from June 2019 to October 2022 in Heilongjiang Province, northeast China.

The complete mitochondrial genome of Prosthogonimus cuneatus and Prosthogonimus pellucidus (Trematoda: Prosthogonimidae), their features and phylogenetic relationships in the superfamily Microphalloidea.

Prosthogonimus cuneatus and Prosthogonimus pellucidus (Trematoda: Prosthogonimidae) are common flukes of poultry and other birds which can cause severe impacts on animal health and losses to the poultry industry. However, there are limited studies on the molecular epidemiology, population genetics, and systematics of Prosthogonimus species. In the present study, the complete mitochondrial (mt) genomes of P.

Integrative Transcriptomics and Proteomics Analyses to Reveal the Developmental Regulation of : A Neglected Trematode With Potential Carcinogenic Implications.

is a neglected zoonotic parasite of the gallbladder and bile duct of poultry, mammals, and humans. It has been widely reported in Asian, including China, Japanese, and Korea, where it is a potential threat to public health. Despite its significance as an animal and human pathogen, there are few published transcriptomic and proteomics data available.

Identification of Myoferlin, a Potential Serodiagnostic Antigen of Clonorchiasis, Immunoproteomic Analysis of Sera From Different Infection Periods and Excretory-Secretory Products of .

Clonorchiasis, which is caused by , is an important foodborne disease worldwide. The excretory-secretory products (ESPs) of play important roles in host-parasite interactions by acting as causative agents. In the present study, the ESPs and sera positive for were collected to identify proteins specific to the sera of (i.

Proteomic Analysis of Excretory and Secretory Products Co-Immunoprecipitated Using Time Course Infection Sera.

is a widespread pathogen that is known for its harmful effects on the health and productivity of ruminant animals. To identify the proteins present in all periods of infection with but not in those with by shotgun liquid chromatography-tandem mass spectrometry (LC-MS/MS), we collected the ESPs and sera of and . In this study, the sheep were artificially infected with and the sera were collected at five different periods: 3 days post-infection (dpi), 7 dpi, 21 dpi, 63 dpi, and 112 dpi.

Phytochemicals protect L02 cells against hepatotoxicity induced by emodin the Nrf2 signaling pathway.

Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified. This study aims to investigate the hepatoprotective effects and potential mechanism of these phytochemicals. The immortalized human hepatocyte cell line L02 was treated with 200 μM emodin for 48 h, and this was used as a hepatocyte injury model.

Complete mitochondrial genomes of Triodontophorus serratus and Triodontophorus nipponicus, and their comparison with Triodontophorus brevicauda.

Triodontophorus serratus and Triodontophorus nipponicus are two of the most common nematodes inhabiting in the large intestine of horse. In the present study, the complete mitochondrial (mt) genome sequences of T. serratus and T.

Exploring time- and frequency- dependent functional connectivity and brain networks during deception with single-trial event-related potentials.

To better characterize the cognitive processes and mechanisms that are associated with deception, wavelet coherence was employed to evaluate functional connectivity between different brain regions. Two groups of subjects were evaluated for this purpose: 32 participants were required to either tell the truth or to lie when facing certain stimuli, and their electroencephalogram signals on 12 electrodes were recorded. The experimental results revealed that deceptive responses elicited greater connectivity strength than truthful responses, particularly in the θ band on specific electrode pairs primarily involving connections between the prefrontal/frontal and central regions and between the prefrontal/frontal and left parietal regions.

[Responses of Nutrients and Chlorophyll a to Water Level Fluctuations in Poyang Lake].

As one of the few remaining lakes that are freely connected with the Yangtze River, Poyang Lake exhibits a unique aquatic ecology which is different from the disconnected lakes. In order to study the mechanism of limnological responses to water level fluctuations (WLFs), samples were collected weekly over 10 months from September 2011 to December 2012 in Xingzi and Duchang, and the effect of fluctuations in water level on nutrients and phytoplankton chlorophyll a (Chla) concentrations was investigated in Poyang Lake. Chla concentrations were strongly related to WLFs, with higher Chla concentrations in the higher water phase.

Comparative analyses of the complete mitochondrial genomes of the two murine pinworms Aspiculuris tetraptera and Syphacia obvelata.

Pinworms Aspiculuris tetraptera and Syphacia obvelata are important parasitic nematodes of laboratory mice, rat and other rodents. However, the mitochondrial (mt) genome of these parasites have not been known yet. In the present study, the complete mt genomes of A.

De novo transcriptomic analysis of the female and male adults of the blood fluke Schistosoma turkestanicum.

Background: Schistosoma turkestanicum is a parasite of considerable veterinary importance as an agent of animal schistosomiasis in many countries, including China. The S. turkestanicum cercariae can also infect humans, causing cercarial dermatitis in many countries and regions of the world.

The complete mitochondrial genome of Metorchis orientalis (Trematoda: Opisthorchiidae): Comparison with other closely related species and phylogenetic implications.

Metorchis orientalis (Trematoda: Opisthorchiidae) is an important trematode infecting many animals and humans, causing metorchiasis. In the present study, the complete mitochondrial (mt) genome of M. orientalis was sequenced.