Publications by authors named "Jun-Fen Wei"
Article Synopsis
- Delirium is a serious brain condition often seen in the elderly, which can increase the risk of developing dementia later on, but its exact causes are not well understood.
- Researchers compared three mouse models of delirium created by surgical anesthesia, inflammation, and neurotransmitter modulation, discovering that certain substances affected brain activity similarly to what is seen in delirium patients.
- The study found that injecting mice with scopolamine caused temporary cognitive issues and increased activity without damaging cholinergic neurons, but it did disrupt hippocampal synapse functions, helping to shed light on how delirium might start.
