Publications by authors named "Jun-Fei Zhu"
Dual inhibition of vascular endothelial growth factor and epidermal growth factor receptor (EGFR) signaling pathways offers the prospect of improving the effectiveness of EFGR-targeted therapy. In this phase 3 study (ClinicalTrial.gov: NCT04028778), 315 patients with treatment-naïve, EGFR-mutated, advanced non-small cell lung cancer (NSCLC) were randomized (1:1) to receive anlotinib or placebo plus gefitinib once daily on days 1-14 per a 3-week cycle.
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- This systematic review explores the relationship between oral microbiome changes (dysbiosis) and the development of oral epithelial dysplasia (OED), a condition that can lead to cancer.
- Researchers analyzed ten case-control studies from various databases, finding that microbiome diversity was inconsistent, with some studies showing increased levels of certain bacteria like Bacteroidetes and Fusobacterium in OED patients, while others noted reduced levels of Streptococcus compared to healthy controls.
- The findings indicate significant variability across studies, suggesting that more research is needed to better understand the oral microbiome's role in OED and its potential link to cancer development.
Reported here is a new [CuI] cluster-based coordination polymer, namely [CuI(bib)]·n(DMF) (1, bib = 1,4-bis(imidazolyl)butane, DMF = N,N'-dimethylformamide), which was synthesized by the self-assemble reaction of CuI, bib and KI under solvothermal conditions. Remarkably, compound 1 shows promising photocatalytic performance toward to the degradation of MB solution under visible light irradiation. For the COPD treatment, the ELISA detection kit was conducted to determine the content of INF-γ released by the respiratory tract mucosal epithelial cells.
View Article and Find Full Text PDFAims: To explore the differences in salivary BPI fold containing family A, member 1 (BPIFA1) concentration among type 2 diabetes mellitus (T2DM) subjects with various severities of chronic periodontitis and to determine whether BPIFA1 in saliva can be used as a potential biomarker of T2DM.
Methods: Unstimulated saliva samples were collected from 44 subjects with T2DM and 44 without T2DM (NDM). Additionally, demographic data and general health parameters, including fasting blood glucose (FBG) and body mass index (BMI), were collected.