Publications by authors named "Jun Zhai"

Article Synopsis
  • The study investigates the role of the zona pellucida (ZP) in oocyte and embryo development, highlighting the lack of clinical treatment guidelines for patients with abnormal ZP (ZPA).
  • A total of 185 ZPA patients and 222 normal ZP patients were analyzed, revealing that ZPA patients experienced poorer IVF outcomes and various hormonal differences.
  • The research identified subcategories of ZPA based on oocyte characteristics and demonstrated that laser-assisted hatching of the ZP can improve embryonic development for certain ZPA subgroups.
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Article Synopsis
  • Perfluoroalkyl acids (PFAAs) are widely found in both urban and rural environments, but there is limited understanding of how they accumulate and transfer in aquatic food webs, particularly in urban fringe lakes like Luoma Lake.
  • The study measured concentrations of 15 PFAAs in fish and crustaceans, finding higher levels in the urban area compared to the rural area, with seasonal changes affecting some species but not others.
  • The research highlighted bioaccumulation differences among organisms and noted significant health risks from certain PFAAs (like PFOS and PFOA) for young children, while suggesting strategies for risk mitigation.
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Water level fluctuations in China's Three Gorges Reservoir (TGR) area are typical of many reservoirs and significantly impact water level fluctuation zones (WLFZ), including upstream rivers. Understanding methane oxidation in the TGR-WLFZ is crucial for evaluating the impact of large-scale reservoir construction on global climate change. In this study, we investigated methane oxidation rates in the TGR-WLFZ, focusing on periods of drying and flooding.

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The senescence of bone marrow mesenchymal stem cells (BMSCs) contributes to the development of degenerative skeletal conditions. To date, the molecular mechanism resulting in BMSC senescence has not been fully understood. In this study, we identified a small non-coding RNA, miR-203-3p, the expression of which was elevated in BMSCs from aged mice.

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Urban waterfront areas are dynamic interfaces where human and natural systems converge, forming complex ecosystems that encompass social, economic, and environmental elements. These areas offer ecological benefits and aesthetic experiences. However, a disparity between social aesthetic preferences and vegetation diversity along riverbanks impedes the integration of ecological and aesthetic values.

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Wastewater serves as a vital resource for sustainable fertilizer production, particularly in the recovery of nitrogen (N) and phosphorus (P). This comprehensive study explores the recovery chain, from technology to final product reuse. Biomass growth is the most cost-effective method, valorizing up to 95 % of nutrients, although facing safety concerns.

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The organic matter (OM) and nitrogen in Fresh leachate (FL) from waste compression sites pose environmental and health risks. Even though the constructed wetland (CW) can efficiently remove these pollutants, the molecular-level transformations of dissolved OM (DOM) in FL remain uncertain. This study reports the molecular dynamics of DOM and nitrogen removal during FL treatment in CWs.

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Background: Although fertilization (IVF) in infertile patients with endometrial hyperplasia is common after drug treatment, the pregnancy outcomes are often unsatisfactory. Till date, no studies have reported the outcome of patients with endometrial hyperplasia treated using early-follicular long (EL) protocol and midluteal long (ML) protocol.

Objective: To evaluate the pregnancy outcomes and disease prognosis of patients with endometrial hyperplasia with or without atypia undergoing IVF treatment with EL protocol or ML protocol.

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Prior studies have established a significant correlation between the DNA fragmentation index (DFI) and infertility. Additionally, certain investigations suggest that environmental exposure may serve as an etiological factor impacting semen quality. This study aimed to explore the impact of season, ambient temperature, and weather extremes on the DFI of sperm, along with other relevant parameters.

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Grasslands deliver essential provisioning and regulatory ecosystem services, concomitantly with indispensable cultural services that merit profound consideration. However, grassland cultural ecosystem services (GCES) face a conspicuous knowledge lacuna due to the lack of a unified research framework and quantitative methodology. This study endeavors to fill this gap by quantifying the potential supply and actual demand of GCES, concurrently scrutinizing spatial congruencies and disparities between GCES supply and demand in Inner Mongolia Autonomous Region (IMAR), China.

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Over the past three decades, there has been a significant global climate change characterized by an increase in the intensity and frequency of extreme climate events. The vegetation status in Qinghai Province has undergone substantial changes, which are more pronounced than other regions in the Qinghai-Tibet Plateau. However, a clear understanding of the response characteristics of plateau vegetation to extreme climate events is currently lacking.

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Periodic and significant water level fluctuations within the Three Gorges Reservoir (TGR) create a complex water level fluctuation zone (WLFZ) that can significantly influence greenhouse gas emissions. However, the scarcity of comprehensive studies investigating long-term monitoring and analysis of CH flux patterns and underlying mechanisms concerning water level variations, environmental characteristics, and microbial communities has limited our understanding. This study conducted a four-year monitoring campaign to examine in situ CH emissions from three representative sampling sites.

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Study Question: Can emergency vitrification protect embryos and oocytes during natural disasters or other events that prevent normal practice to achieve satisfactory embryonic development and clinical outcomes at a later time?

Summary Answer: Emergency vitrification of oocytes and Day 0-Day 5 (D0-D5) embryos during disasters is a safe and effective protective measure.

What Is Known Already: When some destructive events such as floods, earthquakes, tsunamis, and other accidents occur, emergency vitrification in embryo laboratories to protect human embryos, oocytes, and sperm is one of the important measures of an IVF emergency plan. However, there are few detailed reports on emergency vitrification in a state of disaster, especially about oocytes and D0 zygotes.

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Microplastics (MPs) are ubiquitous pollutants that significantly threaten organisms and ecosystems. Constructed wetlands (CWs), a nature-based treatment technology, can effectively remove MPs from wastewater. However, the responses of CWs when exposed to MPs remain unclear.

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The Anammox and Sulfate Reduction Ammonium Oxidation processes were compared in two granular sequencing batch reactors operated for 160 days under anammox conditions. It was hypothesized that increasing the concentration of SO may positively influence the rate of N removal under anaerobic conditions and it was tested whether SO reduction and anammox occur independently or are related to each other. The cooperation of N-S cycles by increasing the concentration of influent SO to 952 mg S/L in the second reactor, a higher ammonium utilization rate and sulfate utilization rate was achieved compared to the first reactor, i.

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The normalized differential vegetation index (NDVI) for Landsat is not continuous on the time scale due to the long revisit period and the influence of clouds and cloud shadows, such that the Landsat NDVI needs to be filled in and reconstructed. This study proposed a method based on the genetic algorithm-artificial neural network (GA-ANN) algorithm to reconstruct the Landsat NDVI when it has been affected by clouds, cloud shadows, and uncovered areas by relying on the MODIS characteristics for a wide coverage area. According to the self-validating results of the model test, the RMSE, MAE, and R were 0.

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Forage supply has been stressed due to the rapid increase in China's livestock consumption. However, the long-term dynamics of the relationships between forage demand and multi-sourced supply are not understood. Here, we examine the annual forage demand, or practical carrying capacity (PCC), and supply, or theoretical carrying capacity (TCC) from 2000 to 2019 in China.

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Background: We aimed to compare the clinical and perinatal outcomes of patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment with either an early-follicular long-acting gonadotropin-releasing hormone agonist (GnRH-a) long protocol (EFLL) or a midluteal short-acting GnRH-a long protocol (MLSL).

Methods: This single-center, retrospective study, included patients with PCOS who underwent IVF/ICSI from January 2013 to June 2019 at the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. Patients underwent either MLSL (1179 cycles) or EFLL (2390 cycles).

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Objective: To investigate whether seasonal variations and meteorological factors influence pregnancy outcomes in women undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment.

Design: Retrospective cohort study.

Setting: University-affiliated reproductive medical center.

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Objective: We aimed to analyze whether elevated progesterone levels on the day before ovulation affected pregnancy outcomes in natural cycles of frozen thawed embryo transfer (NC-FET).

Methods: A retrospective analysis was conducted in a public university hospital. Data on clinical pregnancy, live birth, ectopic pregnancy, and miscarriage rates were collected, along with other patient data.

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Objective: This study aimed to evaluate potential predictors for recovery time in pregnant patients with moderate to severe ovarian hyperstimulation syndrome (OHSS).

Methods: A total of 424 pregnant patients with moderate to severe OHSS who underwent fertilization (IVF)/intracytoplasmic sperm injection (ICSI) were retrospectively identified. The clinical features and laboratory findings within 24 h after admission were collected.

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Background: Studies have shown that abnormalities in the decidualization process were closely related to recurrent implantation failure (RIF). Prokineticin 2 (PK2) is a secreted protein with angiogenic and tissue remodeling functions but its role in the endometrium is unknown.

Methods: PK2 levels and its receptor PKR1 mRNA and protein levels in mid-secretory endometrium from normal and RIF women were examined by real-time PCR and western blotting, respectively.

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Study Objective: Any abnormality of the uterine cavity can result in reduced endometrial receptivity, which negatively affects embryo implantation and leads to lower clinical pregnancy rates. The effects of improved uterine cavity environment on in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI)-embryo transfer (ET) treatment outcome are unclear. This study aimed to investigate the impact of improved uterine cavity abnormalities on the pregnancy outcomes of infertile patients undergoing IVF/ICSI-ET.

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Background: Previous studies have described the effects of different drugs in preventing ovarian hyperstimulation syndrome (OHSS). However, the efficacies of those drugs in preventing OHSS remain inconclusive.

Methods: We searched the PubMed, Web of Science, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) databases.

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The COVID-19 pandemic has led to tremendous impacts on human lives and society, which are not only because of negative effects on people's mental health due to isolation policies and physical distance for mitigating the spread of SARS-CoV-2, but also because the incident post-acute sequelae of the coronavirus will cause mental disorders. A green environment is a health resource, which cannot only benefit human physical and mental health, but also increases biodiversity, contributes to flood mitigation, and cools urban areas. A home garden, as a kind of small green space, can provide ecosystem services with eco-healing functions in reducing mental stress during the isolation period of the COVID-19 pandemic through the garden itself and physical activities in it.

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