Publications by authors named "Jun Yu Lee"
The ability to detect low level DNA brings with it the uncertainty of whether the detected DNA is a result of transfer. To address this uncertainty, a simulation study was conducted in which a mock illicit drug packet was placed into the personal bags of individuals. When the average transit time of the packets was increased from around 2 h to more than 14 h, the percentage of the DNA profiles recovered from the packets which could be attributed to the individuals increased greatly from 5.
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- The importance of DNA evidence in crime scenes is being re-evaluated, focusing on how long it lasts in different environments rather than just its presence.
- The study investigates how long DNA from blood and skin cells lasts in Singapore's tropical climate, exploring both outdoor and indoor conditions.
- Results show that DNA outside can degrade quickly due to rain, while DNA indoors remains more stable, helping law enforcement and courts understand DNA's relevance in various environments.
In lipid storage diseases, the intracellular trafficking of sphingolipids is altered by conditions of aberrant cholesterol accumulation. Drosophila has been used recently to model lipid storage diseases, but the effects of sterol accumulation on sphingolipid trafficking are not known in the fly, and the trafficking of sphingolipids in general has not been studied in this model organism. Here, we examined the uptake and intracellular distribution of a fluorescent glycolipid analog, BODIPY-lactosyl-ceramide, in Drosophila neurons.
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