Publications by authors named "Jun Yokoi"
Bilateral congenital cholesteatoma (BCC) is rare among congenital cholesteatoma (CC) cases, and bilateral surgery poses a significant psychophysical burden on pediatric patients. Here, we present 2 pediatric cases of BCC that were successfully managed using simultaneous bilateral transcanal endoscopic ear surgery (TEES). The surgical approach provided clear visualization of the middle ear structures, enabling successful cholesteatoma removal with minimal invasiveness and a short operative time.
View Article and Find Full Text PDFIntroduction: Binaural hearing enhances speech intelligibility, source localization, and speech comprehension in noisy environments. Although bilateral cochlear implantation (CI) offers several benefits, concerns arise regarding the risk of bilateral postoperative vestibular dysfunction with simultaneous CI. This study aimed to longitudinally evaluate changes in vestibular function in adult patients who underwent simultaneous bilateral CI using minimally invasive electrodes and surgical techniques.
View Article and Find Full Text PDFObjective: To investigate the isosorbide-induced dehydration effect on the endolymphatic space by intratympanic administration of isosorbide.
Background: Isosorbide, an osmotic diuretic, is used orally as a typical conservative therapy for Menière's disease (MD) in Japan. The dehydration effect occurs 6 hours after isosorbide ingestion.
Kenny-Caffey syndrome type 2 (KCS2) is an extremely rare skeletal disorder involving hypoparathyroidism and short stature. It has an autosomal dominant pattern of inheritance and is caused by variants in the FAM111 trypsin-like peptidase A () gene. This disease is often difficult to diagnose due to a wide range of more common diseases manifesting hypoparathyroidism and short stature.
View Article and Find Full Text PDFArticle Synopsis
- Genetic testing has become a standard option for diagnosing congenital or early-onset hearing loss, but it's less common for late-onset cases due to their complexity and lower diagnostic rates.
- A study analyzed 48 Japanese patients with late-onset bilateral sensorineural hearing loss, finding that 60.4% had identifiable genetic causes, indicating a significant genetic component in these cases.
- The study also highlighted two unique cases with specific genetic variants, suggesting the importance of comprehensive genetic testing for accurate diagnosis and better treatment options for late-onset hearing loss patients.
Objective: To present our results of the external auditory canal (EAC) reconstruction procedure using rolled-up full-thickness skin graft with tympanoplasty after lateral temporal bone resection (LTBR) for early-stage EAC carcinoma.
Patients And Methods: A retrospective review of 15 patients who had undergone LTBR with reconstruction of the EAC for T1 and T2 EAC cancer between 2016 and 2020.
Results: Postoperative mean air-bone gap was 30.