Publications by authors named "Jun Yan Xi"

Aims: The association between lifestyle and metabolic dysfunction-associated steatotic liver disease (MASLD) has been well documented. However, evidence is still limited from vulnerable populations, especially middle-aged and elderly adults with comorbid hypertension and diabetes, who are at higher risk of developing MASLD than the general population. We aimed to examine the potential causal links of a healthy lifestyle with the risk of MASLD in this vulnerable population.

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Background: As population aging intensifies, it becomes increasingly important to elucidate the casual relationship between aging and changes in population health. Therefore, our study proposed to develop a systematic attribution framework to comprehensively evaluate the health impacts of population aging.

Methods: We used health-adjusted life expectancy (HALE) to measure quality of life and disability-adjusted life years (DALY) to quantify the burden of disease for the population of Guangzhou.

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Article Synopsis
  • The study looked at how mental health issues and everyday life affect violent behavior in people with schizophrenia.
  • Researchers analyzed data from 1,664 patients to see how their symptoms and real-life functioning connected before and after violence.
  • Results showed that after experiencing violence, connections between symptoms and daily life weakens, suggesting that this could be an early warning sign for future violence.
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Objective: In the context of aging, Chinese families consisting of more than three generations (grandparents, parents, children) are the norm. The second generation (parents) and other family members may establish a downward (contact only with children) or two-way multi-generational relationship (contact with children and grandparents). These multi-generational relationships may have the potential effect on multimorbidity burden and healthy life expectancy in the second generation, but less is known about the direction and intensity of this effect.

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Article Synopsis
  • This article analyzes how reducing disability and premature death from noncommunicable diseases (NCDs) can improve health-adjusted life expectancy (HALE) for individuals aged 30 to 70.
  • Utilizing data from the Global Burden of Disease Study 2019, the study evaluates three future scenarios related to achieving health goals concerning NCDs across various income levels.
  • The findings show that higher-income groups experience the largest potential increases in HALE, particularly from interventions targeting cancer and cardiovascular diseases, indicating that addressing both mortality and disability is crucial for enhancing overall health outcomes globally.
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Background: Quantitative attribution of the burden of disease due to population aging is an important part of setting meaningful global health priorities. This study comprehensively examines the burden of disease attributable to population aging in 188 countries from 1990 to 2019, incorporates a comprehensive range of diseases, and projects the burden of disease due to population aging till 2050.

Methods: We extracted data from 1990 to 2019 for 188 countries from the Global Burden of Disease Study 2019.

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Article Synopsis
  • The study explores the relationship between megacity expansion and the gap between health-adjusted life expectancy (HALE) and overall life expectancy (LE) in Guangzhou, China.
  • Despite increases in both LE and HALE, the gap between them is widening, indicating a decline in quality of life.
  • Factors like personal wealth, population growth, urbanization, and healthy aging are crucial for narrowing this gap, suggesting that multiple social determinants should be considered in public health planning.
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