Extended full-thickness transanal local excision to treat ultra-low rectal cancer: an initial clinical exploration.

Objective: To investigate the feasibility of extended full-thickness transanal local excision for rectal cancers invading anorectal junction.

Methods: Four patients with small (size ≤3cm) unfixed rectal cancer, which extended into the upper anal canal, were submitted to transanal local excision with a dissection plane extended to the striated muscle layer around the upper anal canal, so that a portion of striated muscle beneath or around the tumor was excised en bloc with the anorectal wall. The defect in the anorectal wall was laid open to granulate and epithelize.

Cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations.

Purpose: Studies investigating the association between genetic polymorphism of cyclin D1 (CCND1) G870A and risk of colorectal cancer (CRC) reported conflicting results. In order to derive a more precise estimation of the relationship, a meta-analysis was performed.

Materials And Methods: We performed an extensive search of relevant studies and carried out a meta-analysis, including 20 studies with 5,975 cases and 8,333 controls, to obtain a more precise estimate.

The cyclin D1 G870A polymorphism and colorectal cancer susceptibility: a meta-analysis of 20 populations.

Purpose: Studies of the association between the cyclin D1 (CCND1) G870A genetic polymorphism and risk of colorectal cancer (CRC) have generated conflicting results. In order to derive a more precise estimation, a meta-analysis was here performed.

Materials And Methods: An extensive search of relevant studies was carried out as a meta-analysis of twenty studies with 5,975 cases and 8,333 controls.

[Transsacral local wide resection for mid-lower rectal tumors].

Objective: To evaluate the efficacy of transsacral local wide resection for mid-lower rectal tumors.

Methods: Clinical data of 133 patients undergone transsacral local wide resection for mid-lower rectal tumors between September 1994 and September 2005 were analyzed retrospectively.

Results: No patient died during operation.

[Diagnosis and treatment of anorectal malignant melanoma--a report of 22 cases with literature review].

Background & Objective: Anorectal malignant melanoma (AMM) is an aggressive malignant tumor, and its treatment still remains controversial. This study was to summarize our experience on diagnosis and treatment of AMM.

Methods: Clinicopathologic records, including clinical feature, diagnosis, operation patterns, and prognosis, of 22 patients with AMM, treated in Jiangsu Provincial Cancer Hospital from 1977 to 2003, were analyzed retrospectively with literature review.