Measurements of acoustic particle velocity in a coaxial duct and its application to a traveling-wave thermoacoustic heat engine.

We present theoretical solutions, based on linear acoustic theory, for axial acoustic particle velocity in an annular region of a coaxial duct. The solutions are expressed in terms of two non-dimensional parameters h/δ(ν) and R; h and δ(ν), respectively, represent the half of the spacing between two concentric ducts and the characteristic length given by kinematic viscosity of the gas and angular frequency of acoustic oscillations, and R is the radius ratio of the ducts. The validity of the solutions was verified by direct measurements using a laser Doppler velocimeter.

Multicenter phase II study of weekly paclitaxel plus S-1 combination chemotherapy in patients with advanced gastric cancer.

Background: A multicenter phase II study was conducted to evaluate the efficacy and safety of a combination regimen of weekly paclitaxel plus S-1 in patients with advanced gastric cancer.

Methods: Patients with previously untreated metastatic or recurrent gastric cancer received intravenous paclitaxel 50 mg/m(2) on days 1, 8, and 15, plus oral S-1 40 mg/m(2) b.i.

Phase I study of a combination of s-1 and weekly paclitaxel in patients with advanced or recurrent gastric cancer.

Objective: A phase I study of weekly intravenous paclitaxel combined with a fixed dose of S-1, a dihydropyrimidine-dehydrogenase-inhibitory oral fluoropyrimidine, was conducted for patients with advanced or recurrent gastric cancer (ARGC). Endpoints of this study were to examine the toxicity profile OF this regimen and to determine the recommended dose (rd) of paclitaxel.

Methods: S-1 was fixed at a dose of 80 mg/m(2) per day and was administered for 2 weeks (days 1--14) followed by a 2-week rest.