Publications by authors named "Jun Il Yoo"

Introduction: Grip strength serves as a significant marker for diagnosing and assessing sarcopenia, particularly in elderly populations. The study aims to explore the relationship between individual thigh muscle volumes and grip strength, leveraging advanced AI-based UNETR segmentation techniques for accurate muscle volume assessment.

Methods: The study included 49 participants from a cohort of 478 patients diagnosed with hip fractures at Gyeongsang National University Hospital.

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Background: Dual energy X-ray absorptiometry (DXA) is the gold standard for diagnosing sarcopenia. However, comparative studies using bioelectrical impedance analysis (BIA) would be required in the Korean population. This study aimed to evaluate the correlation between total-body bone density measuring devices (Hologic and GE Lunar) and a bioelectrical impedance measurement device (InBody 970) as well as the correlation between upper body muscle mass.

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Background: The accurate segmentation of spine muscles plays a crucial role in analyzing musculoskeletal disorders and designing effective rehabilitation strategies. Various imaging techniques such as MRI have been utilized to acquire muscle images, but the segmentation process remains complex and challenging due to the inherent complexity and variability of muscle structures. In this systematic review, we investigate and evaluate methods for automatic segmentation of spinal muscles.

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Background: Hip fractures are a common and debilitating condition, particularly among older adults. Loss of muscle mass and strength is a common consequence of hip fractures, which further contribute to functional decline and increased disability. Assessing changes in individual thigh muscles volume in follow-up patients can provide valuable insights into the quantitative recovery process and guide rehabilitation interventions.

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Many older patients with COVID-19 likely have co-morbid osteoporosis. We investigated the clinical outcomes of COVID-19 patients with osteoporosis. This was a retrospective cohort study using national claims data from Korea encoded in the common data model.

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Background: As recognized by the World Health Organization in 2016 with its inclusion in the International Classification of Diseases, Tenth Revision as M62.84, and by South Korea in 2021 as M62.5, the diagnostic guidelines for sarcopenia vary globally.

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  • Hemiarthroplasty is a common treatment for displaced femoral neck fractures in elderly patients, but it carries a risk of dislocation; a new method called the posterior approach with inferior capsulotomy (PAICO) was introduced to improve stability.
  • A study compared 25 patients treated with PAICO to a historical control group of 3,477 patients who had a conventional approach and found no dislocations in the PAICO group versus a 1.3% rate in the control group.
  • The PAICO technique showed similar operation times and complication rates, and it is recommended for surgeons seeking to minimize dislocation risks in knee surgeries.
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  • Basicervical femoral neck fractures (FNFs) are rare but unstable, leading to a higher chance of fixation failure after surgery.
  • This study analyzed 77 patients with basicervical FNFs to compare two treatment methods: multiple cannulated screws (MCS) and fixed angle devices (FAD).
  • Results showed a significantly higher reoperation rate for MCS (23.5%) compared to FAD (2.8%), suggesting that FAD might be the better option for treating these fractures.
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Templating is essential in hip arthroplasty preparation, facilitating implant size prediction and surgical rehearsal. It ensures the selection of suitable implants according to patient anatomy and disease, aiming to minimize post-operative complications. Various templating methods exist, including traditional acetate templating on both analog and digital images, alongside digital templating on digital images, which is categorized into 2D and 3D approaches.

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Background: As the population ages, the rates of hip diseases and fragility fractures are increasing, making total hip arthroplasty (THA) one of the best methods for treating elderly patients. With the increasing number of THA surgeries and diverse surgical methods, there is a need for standard evaluation protocols. This study aimed to use deep learning algorithms to classify THA videos and evaluate the accuracy of the labelling of these videos.

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The study aims to develop a deep learning based automatic segmentation approach using the UNETR(U-net Transformer) architecture to quantify the volume of individual thigh muscles(27 muscles in 5 groups) for Sarcopenia assessment. By automating the segmentation process, this approach improves the efficiency and accuracy of muscle volume calculation, facilitating a comprehensive understanding of muscle composition and its relationship to Sarcopenia. The study utilized a dataset of 72 whole thigh CT scans from hip fracture patients, annotated by two radiologists.

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Objective: Patients with Parkinson's disease (PD) have an increased risk of sarcopenia which is expected to negatively affect gait, leading to poor clinical outcomes including falls. In this study, we investigated the gait patterns of patients with PD with and without sarcopenia (sarcopenia and non-sarcopenia groups, respectively) using an app-derived program and explored if gait parameters could be utilized to predict sarcopenia based on machine learning.

Methods: Clinical and sarcopenia profiles were collected from patients with PD at Hoehn and Yahr (HY) stage ≤ 2.

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Age-related sarcopenia, resulting from a gradual loss in skeletal muscle mass and strength, is pivotal to the increased prevalence of functional limitation among the older adult community. The purpose of this meta-analysis of individual patient data is to investigate the difference in health-related quality of life between sarcopenic individuals and those without the condition using the Sarcopenia Quality of Life (SarQoL) questionnaire. A protocol was published on PROSPERO.

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: Hip fractures are commonly found in elderly patients, and often result in chronic pain and decreased physical function, as well as worsening of overall health. It is known that early surgical intervention during the acute phase and rehabilitation are important for improving clinical outcomes for these patients. However, the importance of management for improving the quality of life of these patients is becoming more emphasized.

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Article Synopsis
  • The study investigated bone turnover markers (BTMs) - CTX, P1NP, and osteocalcin - in Korean patients with osteoporosis through a multicenter clinical analysis.
  • It focused on pre- and post-menopausal women and men, collecting demographic data and measuring BTM levels, while excluding patients without sufficient test results.
  • Results showed significant BTM levels in both genders, with teriparatide increasing P1NP and denosumab decreasing CTX, providing valuable data for future bone health assessments in Koreans.
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  • The increase in centenarians has led to a rise in hip fractures, which can significantly affect their quality of life and incur high medical costs, yet there is limited research on their outcomes.
  • A study observed 68 centenarian hip fracture patients over a period from 2004 to 2019, with 56 patients included for a year-long follow-up, assessing various health metrics and outcomes.
  • Results showed a high mortality rate of 39.3% at 1 year post-surgery, with pre-injury mobility being a significant risk factor for mortality, as only 16.1% were able to walk outdoors after surgery.
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Periprosthetic joint infection (PJI) can be diagnosed to characterize the microorganisms constituting a biofilm, which is an essential procedure for proper treatment. The gold standard method for detecting and identifying the causative microorganism is culture of microorganisms from patients-derived sample.; however, this method takes a long time and has low sensitivity.

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Osteoporosis is a health condition that involves weak bone mass and a deteriorated microstructure, which consequently lead to an increased risk of bone fractures with age. In elderly people, a fracture attributable to osteoporosis elevates mortality. The objective of this review was to examine the effects of macronutrients on bone mineral density (BMD), bone turnover markers (BTMs), and bone fracture in elderly people based on human studies.

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Background: The relationship between physical function, musculoskeletal disorders and sarcopenia is intricate. Current physical function tests, such as the gait speed test and the chair stand test, have limitations in eliminating subjective influences. To overcome this, smart devices utilizing inertial measurement unit sensors and artificial intelligence (AI)-based methods are being developed.

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Background: The purpose of this study was to verify the accuracy and validity of using machine learning (ML) to select risk factors, to discriminate differences in feature selection by ML between men and women, and to develop predictive models for patients with osteoporosis in a big database.

Methods: The data on 968 observed features from a total of 3,484 the Korea National Health and Nutrition Examination Survey participants were collected. To find preliminary features that were well-related to osteoporosis, logistic regression, random forest, gradient boosting, adaptive boosting, and support vector machine were used.

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Background: Dual energy X-ray absorptiometry (DXA) is a preferred modality for screening or diagnosis of osteoporosis and can predict the risk of hip fracture. However, the DXA test is difficult to implement easily in some developing countries, and fractures have been observed before patients underwent DXA. The purpose of this systematic review is to search for studies that predict the risk of hip fracture using artificial intelligence (AI) or machine learning, organize the results of each study, and analyze the usefulness of this technology.

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  • - Sarcopenia, a condition affecting elderly individuals, leads to decreased muscle mass annually and is influenced by factors like diet, exercise, and lifestyle; this study explores the connection between muscle mass traits and genetically influenced epigenetic factors using data from the Korean Genome and Epidemiology Study (KOGES).
  • - The researchers analyzed participants by adjusting muscle mass index (MMI) through three different methods, identifying DNA methylation patterns in the top and bottom 30% of muscle mass and comparing various demographic and health metrics between groups.
  • - Enrichment analysis of DNA methylation results revealed particular pathways associated with sarcopenia, showing varied significant pathways based on both sex and the MMI adjustment method used, such as
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  • The study aimed to explore the demographic and radiological factors associated with lesser trochanter splitting (LTS) irreducible intertrochanteric fractures and assess clinical outcomes for patients treated with dynamic hip screws (DHS).
  • A total of 13 cases (3.1% of intertrochanteric fractures) were analyzed, revealing a mean patient age of 50.4 years, predominantly male involvement, and fractures largely resulting from high-energy trauma.
  • All patients achieved bone union post-surgery, with no complications reported, highlighting that reduction quality varied but was generally acceptable in the majority of cases.
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Background: Teriparatide is an effective anabolic agent used in the treatment of severe osteoporosis. In addition, it is also used to promote fracture healing. The purpose of this double-blind randomized controlled trial was to evaluate the influence of weekly teriparatide administration on bone formation in hip fracture patients.

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