Climate-Influenced Ecological Memory Modulates Microbial Responses to Soil Moisture.

Long-term climatic differences shape the ecological memory of soil bacterial communities, which refers to the ability of past events to influence current environmental responses. However, their ecological mechanisms and consequences for bacterial responses to current environmental changes remain largely unknown, particularly in terms of temporal dynamics. Therefore, soil bacterial communities in the arid (Lhasa River Basin) and humid (Nyang River Basin) grasslands of the Qinghai-Tibet Plateau were compared to explore their temporal dynamics in response to current soil moisture and the resulting ecological consequences.

[Staged treatment for 32 cases of ankylosing spondylitis with different acupuncture methods based on theory].

Objective: To observe the clinical efficacy of different acupuncture methods in the treatment of ankylosing spondylitis (AS) at different stages.

Methods: Thirty-two patients with AS were treated with acupuncture at points (tendon focus), triple acupuncture method was used in the acute phase, accompanied needling method was used in the remission phase, once a day, 5 times a week for 4 weeks. The Bath ankylosing spondylitis disease activity index (BASDAI) score, Bath ankylosing spondylitis functional index (BASFI) score and TCM symptom grade quantitative standard score before and after treatment were observed, and the efficacy was evaluated.

Eutrophication-induced shifts cause diverse responses in the phoD community of a plateau freshwater lake.

Eutrophication is a critical environmental challenge affecting lakes globally. Mitigating trophic level under endogenous phosphorus release is an unsolved problem in eutrophic lakes. However, understanding the dynamics and assembly of microbial communities encoding the alkaline phosphatase (phoD community) and their responses during trophic transitions in eutrophic lakes is limited.

Severe weight loss during PD-1 treatment is a risk sign of poor prognosis for advanced GC patients.

Objective: To verify whether severe weight loss is a reasonable risk sign for the effect of PD-1 treatment in advanced gastric cancer (GC) patients.

Methods: 127 metastatic or recurrent GC patients treated with PD-1 inhibitors in Xuzhou Central Hospital were involved in this study. Two cohorts with different variables were built; one was used to reveal the relationship between body weight loss and overall survival (OS), and the other was used to find which body composition contributed to the weight loss.

Distinct species turnover patterns shaped the richness of antibiotic resistance genes on eight different microplastic polymers.

Elucidating the formation mechanism of plastisphere antibiotic resistance genes (ARGs) on different polymers is necessary to understand the ecological risks of plastisphere ARGs. Here, we explored the turnover and assembly mechanism of plastisphere ARGs on 8 different microplastic polymers (4 biodegradable (bMPs) and 4 non-biodegradable microplastics (nMPs)) by metagenomic sequencing. Our study revealed the presence of 479 ARGs with abundance ranging from 41.

Expression and clinical significance of CA125, CA153 and CEA in nipple discharge of breast cancer patients.

Background: It is an important clinical means to identify benign and malignant breast diseases caused by nipple discharge through the detection and analysis of components in nipple discharge. This study was aimed to test the expression and clinical significance of carbohydrate antigen 125 (CA125), carbohydrate antigen 153 (CA153) and carcinoembryonic antigen (CEA) in nipple discharge of breast cancer patients.

Methods: From January 2017 to December 2018, 86 patients with invasive ductal carcinoma of the breast with nipple discharge (breast cancer group) and 50 patients with ordinary breast duct hyperplasia with nipple discharge (benign control group) were selected, and the levels of CA125, CA153 and CEA in nipple discharge and serum were detected by electrochemiluminescence immunoassay.

Automated extraction of Tridacna shell growth patterns via machine learning for enhanced paleoclimate/paleoweather research.

Tridacna spp. are valuable archives for paleoclimate and paleoweather research due to their distinct daily growth patterns and the sensitivity of the daily growth patterns to environment changes. However, manually identifying daily growth lines and measuring the daily growth increment width (DGIW) of Tridacna shells from Laser Scanning Confocal Microscopy (LSCM) images is a tedious task that has become a significant barrier to Tridacna studies.

Diversity and biogeography of bacterial community in the Ili River network varies locally and regionally.

Microorganisms in rivers indeed play a crucial role in nutrient cycling within aquatic ecosystems. Understanding the assembly mechanisms of bacterial communities in river networks is essential for predicting their special composition and functional characteristics in natural rivers. This study employed 16S rRNA gene amplicon sequence variation (ASVs) to scrutinize the bacterial community within the uniquely topographical Ili River network.

Reconstruction of ENSO variability using the standardized growth index of a Tridacna shell from Yongshu Reef, South China Sea.

El Niño-Southern Oscillation (ENSO) is the strongest signal of global interannual climate anomaly and reconstructing past ENSO variations using high-resolution paleoclimate archives can improve our understanding of ENSO variability, as well as improve our ability to predict future climate changes. Here, a daily resolution standardized growth index (SGI) was established using a giant clam (Tridacna spp.) shell specimen MD2 (life span: 1994-2013 CE), collected from the Yongshu Reef, southern South China Sea (SCS).

Associations between Alzheimer's disease biomarkers and postoperative delirium or cognitive dysfunction: A meta-analysis and trial sequential analysis of prospective clinical trials.

Background: The relationship between Alzheimer's disease biomarkers and postoperative complications, such as postoperative delirium (POD) and postoperative cognitive dysfunction (POCD), remains a subject of ongoing debate.

Objective: This meta-analysis aimed to determine whether there is an association between perioperative Alzheimer's disease biomarkers and postoperative complications.

Design: We conducted a meta-analysis of observational clinical studies that explored the correlation between Alzheimer's disease biomarkers and POD or POCD in patients who have undergone surgery, following PRISMA guidelines.

The threat of micro/nanoplastic to aquatic plants: current knowledge, gaps, and future perspectives.

Plastics have been recognized as an emerging pollutant and have raised global concerns due to their widespread distribution in the environment and potential harm to living systems. However, research on the threat of micro/nanoplastics (MPs/NPs) to the unique group of aquatic plants is far behind, necessitating a comprehensive review to summarize current research progress and identify future research needs. This review explores the sources and distribution patterns of MPs/NPs in aquatic environments, highlighting their uptake by aquatic plants through roots and leaves, and subsequent translocation via the vascular system facilitated by the transpiration stream.

A Quantitative Study of a Directional Heat Island in Hefei, China Based on Multi-Source Data.

Surface urban heat islands (SUHIs) are essential for evaluating urban thermal environments. However, current quantitative studies of SUHIs ignore the thermal radiation directionality (TRD), which directly affects study precision; furthermore, they fail to assess the effects of TRD characteristics at different land-use intensities, on the quantitative studies of SUHIs. To bridge this research gap, this study eliminates the interference of atmospheric attenuation and daily temperature variation factors, in quantifying the TRD based on land surface temperature (LST), from MODIS data and station air temperature data for Hefei (China) from 2010-2020.

Ultraversatile Fluorescent Sensors Based on Two Co/Ni Coordination Polymers for Identifying Various Antibiotics via the Turn-On/Off Effect and Detecting pH.

Because the accurate and rapid detection of antibiotics and pH plays an important role in biological systems and environmental fields, developing suitable and efficient sensors that can simultaneously detect antibiotics and pH has become important. In this work, we successfully designed and synthesized two new one-dimensional coordination polymers based on the mixed ligands L [,'-bis(4-methylpyridin-4-yl)-2,6-naphthalene dicarboxylamide] and HCPG [3-(4-chlorophenyl)glutaric acid], [M(L)(HCPG)(HO)] (M = Co for CP , and M = Ni for CP ), which were structurally characterized by single-crystal X-ray diffraction, infrared spectroscopy, powder X-ray diffraction, and thermogravimetric analysis. CP and CP can be used as ultraversatile fluorescent sensors, which can sense erythromycin (ERY) and oxacillin (OXC) by turn-on fluorescent enhancement and detect furaltadone (FTD) via the turn-off fluorescent quenching effect, separately.

Endophytic Phthalate-degrading Bacillus subtilis N-1-gfp colonizing in soil-crop system shifted indigenous bacterial community to remove di-n-butyl phthalate.

Endophytic bacteria can degrade toxic phthalate (PAEs). Nevertheless, the colonization and function of endophytic PAE-degrader in soil-crop system and their association mechanism with indigenous bacteria in PAE removal remain unknown. Here, endophytic PAE-degrader Bacillus subtilis N-1 was marked with green fluorescent protein gene.

Effect of Negative Pressure Wound Therapy on Surgical Site Infections following Stoma Reversal in Colorectal Surgery: A Meta-Analysis.

Background: Surgical site infections (SSI) are common complications after surgery, which cause other complications and increase medical costs. However, the effect of negative-pressure wound therapy (NPWT) for the prevention of SSI at stoma reversal remains inconclusive, with controversial results. This meta-analysis aimed to evaluate the safety and efficacy of NPWT following stoma reversal in colorectal surgery to prevent SSI and other wound complications.

A new three-dimensional zinc(II) metal-organic framework as a fluorescence sensor for sensing the biomarker 3-nitrotyrosine.

3-Nitrotyrosine (3-NT), an oxidative stress biomarker, is closely associated with various diseases. Thus, rapid and sensitive detection of 3-NT is of great significance for preventing and treating diseases. Herein, we reported a new 3D zinc-based metal-organic framework (Zn-MOF) [Zn(L)(HBTC)] (L = ()-4,4'-(ethene-1,2-diyl)bis[(-pyridin-3-yl)benzamide], HBTC = 1,3,5-benzenetricarboxylic acid), which was structurally characterized by single crystal X-ray diffraction, IR, PXRD and TG.

Effect of Coffee Consumption on Postoperative Ileus after Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials.

Background: Postoperative ileus (POI) is an important complication after elective colorectal surgery, which prolongs hospital stay and increases hospital costs. Coffee has been reported to be beneficial for the recovery of gastrointestinal function. We aimed to investigate the effectiveness of coffee consumption in the treatment of POI, following elective colorectal surgery.

The Effect of a Combined Modified Pectoral and Stellate Ganglion Block on Stress and Inflammatory Response in Patients Undergoing Modified Radical Mastectomy.

Background And Aims: Regional anaesthesia reports to attenuate stress and inflammatory responses associated with surgical resection; however, the effectiveness of combined nerve blocks is less often investigated. We evaluated whether a combination of a pectoral nerve block (PNB) and stellate ganglion block (SGB) is more effective than a PNB alone in reducing these responses in women undergoing modified radical mastectomy (MRM).

Methods: This is a prospective randomized controlled trial.

The Collection and Recognition Method of Music and Dance Movement Based on Intelligent Sensor.

With the popularization and development of Internet of Things technology, a large number of music and dance videos have emerged in all walks of life. In this information age, video communication has become a widespread communication method. In the current music and dance collection process, most of the action frame information of the dance video is repeated, and the stage background and costumes of the dance action are too many to fully express the human body movement information.

Maize root-associated niches determine the response variation in bacterial community assembly and function to phthalate pollution.

Plant root-associated microbiome can be influenced by environmental stress like pollution. However, how organic pollution influences microbial communities in different root-associated niches and plant-microbe interaction remains unclear. We analyzed maize root-associated bacterial communities under stress of di-(2-ethylhexyl) phthalate (DEHP).

Uptake pathways of phthalates (PAEs) into Chinese flowering cabbage grown in plastic greenhouses and lowering PAE accumulation by spraying PAE-degrading bacterial strain.

Uptake pathway and accumulation variation of soil and airborne phthalates (PAEs) in plastic greenhouses by vegetables remains unclear. Here, pot experiments of Chinese flowering cabbage were designed to distinguish root or leaf uptake pathways of PAEs, and investigate the mitigation of spraying PAE-degrading strain in PAE accumulation by vegetables. The results showed that leaves of Chinese flowering cabbage grown in plastic greenhouses absorbed more PAEs from air than those of outside greenhouses.

Presacral Benign Schwannoma Mimics Malignancy on 18F-FDG and 68Ga-FAPI PET/CT.

We present findings of FDG PET/CT and FAPI PET/CT in a 55-year-old woman with a history of black stools and low-back pain. Pelvic CT detected a giant presacral mass that was suspected to be malignant. 18F-FDG and 68Ga-FAPI PET/CT showed that the mass had intense activity.

[Evaluation and Sources of Heavy Metal Pollution in the Surface Soil of the Qaidam Basin].

To understand surface soil heavy metal pollution characteristics, and the spatial distribution and sources of pollution in the main sedimentary features of the Qaidam Basin, a total of 129 topsoil samples(0-10 cm) were collected within a 25 km radius. The concentrations of As, Ba, Cr, Mn, Nb, Ni, Pb, Ti, Zn, Zr, and ten kinds of heavy metals were determined, the degree of contamination and potential sources quantitatively analyzed based on enrichment factors(EFs), the ground accumulation index(), and the absolute principal component-multiple linear regression(APCS-MLR) receptor model. The results showed that the surface soils of the Qaidam Basin have experienced pollution from ten kinds of heavy metals since the 1960s, with varying degrees of enrichment.

Performance of Regression Models as a Function of Experiment Noise.

Background: A challenge in developing machine learning regression models is that it is difficult to know whether maximal performance has been reached on the test dataset, or whether further model improvement is possible. In biology, this problem is particularly pronounced as sample labels (response variables) are typically obtained through experiments and therefore have experiment noise associated with them. Such label noise puts a fundamental limit to the metrics of performance attainable by regression models on the test dataset.

Formation free energy of an i-mer at spinodal.

In statistical mechanics, the formation free energy of an i-mer can be understood as the Gibbs free energy change in a system consisting of pure monomers after and prior to the formation of the i-mer. For molecules interacting via Lennard-Jones potential, we have computed the formation free energy of a Stillinger i-mer [F. H.