Use of oral glucose tolerance testing and HbA1c at 6-14 gestational weeks to predict gestational diabetes mellitus in high-risk women.

Purpose: To study the prediction of gestational diabetes mellitus (GDM) in high-risk pregnant women by testing fasting blood glucose, 1-h(1hPG) and 2-h plasma glucose (2hPG) after an oral glucose tolerance test, and glycated hemoglobin (HbA1c) in early pregnancy (6-14 weeks).

Methods: We recruited 1311 pregnant women at high risk for diabetes from the Obstetrics Clinic of Daxing District People's Hospital between June 2017 and December 2019. The tests performed during the first trimester included fasting blood glucose (FPG), HbA1c, and 75-g oral glucose tolerance test (OGTT) with 1hPG and 2hPG.

Sustainable Development of Industry-Environmental System Based on Resilience Perspective.

The contradiction between industrial development and ecological environment pressure has been becoming progressively severe. Under this circumstance, more attention has been paid to the balance between industrial economic development and environmental deterioration and resource consumption. Thus, this study takes the development of industry and ecological environment change as an interactive system consideration, and comprehensively evaluates the changes of the industrial-environment system on resilience perspective with innovation.

Challenges in the ethics review process of clinical scientific research projects in China.

Purpose: Ethics review processes have become increasingly complex. The objective of this study was to explore the challenges currently faced in ethics reviews of clinical scientific research projects in China, with the goal of standardizing the structure of medical ethics committees and better protecting the rights and interests of research participants.

Methods: We reviewed and comprehensively analyzed the available literature discussing standardized ethics reviews of clinical scientific research projects.

Protective effect of veratric acid on lipopolysaccharide-induced acute lung injury in mice.

Veratric acid, a simple benzoic acid derived from plants and fruits, has been reported to exhibit antibacterial, anti-inflammatory and other important therapeutic activities. The aim of this study was to detect the effects of veratric acid on LPS-induced acute lung injury and to investigate the effects of veratric acid on NF-κB signaling pathway. Male BALB/c mice were pretreated with dexamethasone or veratric acid 1h before intranasal instillation of LPS.

Cloning and biochemical characterization of a novel lipolytic gene from activated sludge metagenome, and its gene product.

In this study, a putative esterase, designated EstMY, was isolated from an activated sludge metagenomic library. The lipolytic gene was subcloned and expressed in Escherichia coli BL21 using the pET expression system. The gene estMY contained a 1,083 bp open reading frame (ORF) encoding a polypeptide of 360 amino acids with a molecular mass of 38 kDa.