Optimization of time to initial vancomycin target trough improves clinical outcomes.

Background: Outcomes data for the efficacy of interventions designed to decrease the time to initial target vancomycin troughs are sparse.

Objective: A vancomycin therapeutic drug monitoring (TDM) program was initiated to reduce the time to initial target troughs and to examine the impact on clinical outcomes.

Methods: Single-center, pre- and post-intervention observational study in a 250 bed teaching facility.