Publications by authors named "Jun Cho"

Introduction: Measles remains a public health concern, particularly among populations with suboptimal vaccination coverage, including immigrants. Understanding the seroprevalence of measles antibodies in immigrant populations is essential to inform tailored vaccination strategies and reduce the risk of measles reintroduction.

Methods: This study evaluated measles IgG seroprevalence among 651 immigrants from 30 countries residing in Gwangju, South Korea.

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  • Ischemia and reperfusion (IR) lead to oxidative stress and excitotoxicity, major factors in neuronal death in the brain, and hyperthermia worsens this damage.
  • A study conducted on gerbils showed that hyperthermic conditions resulted in earlier neuronal death after IR injury compared to normothermic conditions, with significant increases in oxidative stress markers.
  • The research indicated that hyperthermia amplifies neuronal damage in the hippocampal CA1 region by enhancing oxidative stress and excitotoxicity, as evidenced by changes in various protein levels and cell responses.
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Importance: The association between smoking cessation and cardiovascular disease (CVD) risk in relation to cumulative smoking exposure remains poorly understood.

Objective: To evaluate the associations among smoking cessation, lifetime smoking burden, and CVD risk according to the number of years elapsed after smoking cessation.

Design, Setting, And Participants: This retrospective cohort study of the Korean National Health Insurance Service database investigated smoking duration and intensity between January 2006 and December 2008.

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Two-dimensional Ruddlesden-Popper series are an excellent system for tuning physical properties of the perovskite by controlling the layer number (). For instance, bandgap and exciton binding energies of the series gradually increase upon reducing via enhanced quantum and dielectric confinements. Here, we present findings that challenge the anticipated trend in electron-hole exchange interaction within (BA)MAPbBr ( = 1-3), which causes spin-dependent exciton level splitting into bright and dark states, where the latter is partially visible near the surface of the Br-based two-dimensional Ruddlesden-Popper series.

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This study was conducted to develop and validate a deep learning model for delineating intravascular ultrasound (IVUS) images of coronary arteries.Using a total of 1240 40-MHz IVUS pullbacks with 191,407 frames, the model for lumen and external elastic membrane (EEM) segmentation was developed. Both frame- and vessel-level performances and clinical impact of the model on 3-year cardiovascular events were evaluated in the independent data sets.

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  • - This study investigates the link between tuberculosis (TB) and cardiovascular disease (CVD) in South Korea, utilizing data from the Korea National Health and Nutrition Survey and focusing on the 10-year atherosclerotic cardiovascular disorder (ASCVD) risk among TB survivors.
  • - Out of 69,331 participants, 4% were identified as post-TB survivors, showing a significantly higher 10-year ASCVD risk compared to healthy controls—40.46% vs. 24.00%—with factors like age, smoking, income level, diabetes, and depression further contributing to increased CVD risk in this group.
  • - The study concludes that TB survivors have a considerably elevated risk of cardiovascular issues, emphasizing the
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Adherence to lifestyle recommendations is crucial in managing hypertension, independent of medical treatment. This study aimed to evaluate the implementation of adherence to lifestyle recommendations and analyze the trends in adherence to lifestyle recommendations among patients with hypertension in Korea from 2007 to 2021 using the Korea National Health and Nutrition Examination Survey (KNHANES). The study included adults aged ≥20 years.

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Background: Intralesional methotrexate injection (IL-MTX) is an appropriate strategy for treating epithelial crateriform tumors (ECTs) when surgical excision can result in functional or cosmetic defects; however, not all ECTs are responsive to this treatment.

Objective: This study aimed to evaluate the effectiveness of IL-MTX for ECTs and to determine the differences in clinical response according to the pathological features.

Methods: The medical records of patients treated with IL-MTX for their ECTs were retrospectively reviewed.

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Archaeological excavations led by Yung-jo Lee and Jong-yoon Woo were carried out twice at the Sorori paleolithic site, Cheongju, in the Republic of Korea, at the upper stream of the Geumgang river, the Miho riverside. A total of 127 rice seeds were excavated, including 18 ancient rice and 109 Quasi-rice, in 1998 and 2001. At the first excavation, eleven short -type ancient rice and one slender smooth ancient rice with two kinds of Quasi-rice were excavated.

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All-solid-state batteries (ASSBs) possess the advantage of ensuring safety while simultaneously maximizing energy density, making them suitable for next-generation battery models. In particular, sulfide solid electrolytes (SSEs) are viewed as promising candidates for ASSB electrolytes due to their excellent ionic conductivity. However, a limitation exists in the form of interfacial side reactions occurring between the SSEs and cathode active materials (CAMs), as well as the generation of sulfide-based gases within the SSE.

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Phase-pure polycrystalline BaRuMnO was prepared and determined to adopt the noncentrosymmetric polar crystal structure (space group 2) based on results of second harmonic generation, convergent beam electron diffraction, and Rietveld refinements using powder neutron diffraction data. The crystal structure features zigzag chains of corner-shared trimers, which contain three distorted face-sharing octahedra. The three metal sites in the trimers are occupied by disordered Ru/Mn with three different ratios: Ru1:Mn1 = 0.

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  • This study looked at factors that can increase the risk of developing abdominal aortic aneurysm (AAA) among people in South East Wales from 1993 to 2015.
  • Out of nearly 7,000 patients, 275 were found to have AAA, with most of them being older men.
  • The researchers identified several risk factors for AAA, including family history, previous surgeries, heart disease, diabetes, smoking, and more, which can help improve future health screenings.
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  • Sclerotherapy, particularly using bleomycin, is an effective nonsurgical treatment for digital mucous cysts (DMC), showing better side effects compared to traditional agents.
  • A study compared the effectiveness and safety of bleomycin intralesional injection (ILI) to corticosteroid ILI and surgical excision for DMC treatment, finding bleomycin ILI and surgical excision to be more effective than corticosteroids.
  • Patient satisfaction was highest with bleomycin ILI, indicating it's a safe and effective option for DMC management, offering results comparable to surgical excision without significant adverse effects.
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Background: The impact of hypertrophic cardiomyopathy (HCM) on cardiovascular and obstetrical outcomes in pregnant women remains unclear, particularly in Asian populations. This study aimed to evaluate the maternal cardiovascular and obstetrical outcomes in Korean women with HCM.

Methods: Using data from the Korean National Health Insurance Service database, we identified women who gave birth via cesarean section or vaginal delivery after being diagnosed with HCM between 2006 and 2019.

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  • - The REST trial aims to assess the safety and effectiveness of remimazolam for moderate sedation during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), comparing it against standard midazolam treatments.
  • - The study will enroll 330 patients with suspected lung cancer lesions across four university hospitals, randomly assigning them to receive either remimazolam or two types of midazolam for the procedure.
  • - Through this trial, researchers hope to establish improved sedation practices for EBUS-TBNA, potentially enhancing patient experiences and outcomes.
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This study evaluated the association of atherogenic index of plasma (AIP) with platelet reactivity and clinical outcomes according to acute myocardial infarction (AMI). The composite of 3-year adverse outcomes of all-cause death, myocardial infarction, and cerebrovascular accident was evaluated in 10,735 patients after successful percutaneous coronary intervention with drug-eluting stents. AIP was defined as the base 10 logarithm of the ratio of triglyceride to high-density lipoprotein cholesterol concentration.

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Porphyran, a sulfated polysaccharide found in various species of marine red algae, has been demonstrated to exhibit diverse bioactivities, including anti-inflammatory effects. However, the protective effects of porphyran against cerebral ischemia and reperfusion (IR) injury have not been investigated. The aim of this study was to examine the neuroprotective effects of porphyran against brain IR injury and its underlying mechanisms using a gerbil model of transient forebrain ischemia (IR in the forebrain), which results in pyramidal cell (principal neuron) loss in the cornu ammonis 1 (CA1) subregion of the hippocampus on day 4 after IR.

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  • Type A aortic dissection and intramural hematoma are serious conditions that require emergency surgery typically involving cooled body temperatures and cardiopulmonary bypass.
  • This study analyzed the outcomes of different arterial cannulation techniques used during surgery, comparing antegrade and retrograde methods regarding surgical time and ICU stay.
  • Findings showed that while antegrade cannulation led to shorter surgical times and ICU stays, there was no significant difference in 30-day mortality or rates of cerebrovascular accidents between the two methods.
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Background: Congenital insensitivity to pain with anhidrosis (CIPA) is an extremely rare autosomal recessive disorder caused by loss-of-function mutations of the NTRK1 gene, affecting the autonomic and sensory nervous system. Clinical manifestation is varied and includes recurrent fever, pain insensitivity, anhidrosis, self-mutilating behavior, and intellectual disability.

Methods: Clinical and genetic features were assessed in two males and one female with genetically confirmed CIPA using exome or genome sequencing.

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Aucubin, an iridoid glycoside, possesses beneficial bioactivities in many diseases, but little is known about its neuroprotective effects and mechanisms in brain ischemia and reperfusion (IR) injury. This study evaluated whether aucubin exhibited neuroprotective effects against IR injury in the hippocampal CA1 region through anti-inflammatory activity in gerbils. Aucubin (10 mg/kg) was administered intraperitoneally once a day for one week prior to IR.

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  • Venoarterial extracorporeal membrane oxygenation (ECMO) is used for patients in cardiac arrest, with peripheral cannulation methods being preferable for extracorporeal cardiopulmonary resuscitation (ECPR).
  • A study at Daegu Catholic University Medical Center analyzed 99 ECPR patients, comparing surgical cutdown and percutaneous cannulation methods in terms of survival rates and insertion times.
  • Both methods showed similar in-hospital survival rates (36.4% for surgical and 30.3% for percutaneous), but quicker ECMO insertion times were linked to better survival outcomes due to reduced low-flow times during resuscitation.
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