Publications by authors named "Jullietta Lady"
Article Synopsis
- The study focuses on the antibiotic resistance of Staphylococcus aureus, especially its methicillin-resistant strain, which has become a significant health concern during and after the COVID-19 pandemic.
- Researchers aimed to assess the antibacterial effects of Lagerstreomia speciosa, a medicinal plant, against S. aureus and explore the potential of its compound, corosolic acid, to enhance the effectiveness of cefotaxime, a common antibiotic.
- Results demonstrated that corosolic acid and L. speciosa extracts showed antibacterial activity against various strains of S. aureus, with corosolic acid enhancing cefotaxime's action, particularly noted for its synergistic effects and improved bactericidal activity in combination treatments.
The increasing prevalence of antimicrobial resistance (AMR) in Staphylococcus aureus against commonly used antibiotics is a major global health issue. To prevent the emergence of AMR and maintain the desired therapeutic effect, the use of drug combinations in the therapeutic management of infections can be contemplated. This approach allows for the administration of lower antibiotic dosages without compromising the desired therapeutic outcome.
View Article and Find Full Text PDFEugenol, a clove-derived aromatic compound has shown antibacterial activity against many species, including Staphylococcus aureus. Epidemiology studies from the past two decades reported an increased number of healthcare-associated and skin tissue infections due to S. aureus antimicrobial resistance (AMR) including several cases of resistance to β-lactam antibiotics, such as cefotaxime.
View Article and Find Full Text PDFDiabetes mellitus (DM) is a metabolic disorder with growing global incidence, as 387 million people were diagnosed in 2014 with an expected projection of 642 million in 2040. Several complications are associated with DM including heart attack, stroke, kidney failure, blindness, and cancer. The latter is the second leading cause of death worldwide accounting for one in every six deaths, with liver, pancreas, and endometrium cancers are the most abundant among patients with diabetes.
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