Henle Fiber Layer Hemorrhage in Macular Telangiectasia Type 2: Is Right Eye Dominance Coincidence or Consequence?

Purpose: To summarize all reported cases of Henle fiber layer (HFL) hemorrhage in the absence of subretinal neovascularization (SRNV) in patients with macular telangiectasia type 2 (MacTel2) and to propose a mechanism for the right-sided predominance of this unique presentation.

Design: Perspective.

Methods: Collection, review, and analysis of all cases in the literature and in the authors' databases of HFL hemorrhage in MacTel2, including analysis of baseline and follow-up multimodal retinal imaging findings of selected cases.

Genotype and Phenotype Studies in Autosomal Dominant Retinitis Pigmentosa (adRP) of the French Canadian Founder Population.

Purpose: The French Canadian population of Quebec is a unique, well-known founder population with religious, linguistic, and geographic isolation. The genetics of retinitis pigmentosa (RP) in Quebec is not well studied thus far. The purpose of our study was to establish the genetic architecture of autosomal dominant RP (adRP) and to characterize the phenotypes associated with new adRP mutations in Quebec.

Beyond visual acuity: functional outcome and patient satisfaction following treatment for age-related macular degeneration.

Objective: The success of current medical treatments for choroidal neovascular membranes secondary to age-related macular degeneration (AMD) has often been determined anatomically by change in lesion size and cessation of leakage. Measuring the functional success of treatments has most often revolved around visual acuity and has seldom encompassed patients' satisfaction with treatment. Using additional objective and subjective measures to assess the outcome of treatments may provide greater insight into the visual functions that are lost, maintained, or improved during the course of treatment.