Publications by authors named "Julius Fleischhammer"

Objectives: Rheumatoid arthritis (RA) is a common autoimmune disease typically affecting joints symmetrically. A small number of patients develop unilateral and severely destructive wrist arthritis (DWA). The objective of our study was to characterise patients with this type of affection.

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OBJECTIVE Robot-guided pedicle screw placement is an established technique for the placement of pedicle screws. However, most studies have focused on degenerative disease. In this paper, the authors focus on metastatic spinal disease, which is associated with osteolysis.

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Objective: The aim of this study was to develop a rapid diffusion-weighted (DW) magnetic resonance imaging (MRI) technique for whole-brain studies without susceptibility artifacts and measuring times below 3 minutes.

Materials And Methods: The proposed method combines a DW spin-echo module with a single-shot stimulated echo acquisition mode MRI sequence. Previous deficiencies in image quality due to limited signal-to-noise ratio are compensated for (1) by radial undersampling to enhance the flip angle and thus the signal strength of stimulated echoes; (2) by defining the image reconstruction as a nonlinear inverse problem, which is solved by the iteratively regularized Gauss-Newton method; and (3) by denoising with use of a modified nonlocal means filter.

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Background: Although previous studies have described the clinical features of the nervus intermedius (NI), no attempt has yet been made to describe the relationship between the ultrastructural and electrophysiological characteristics of the nervus intermedius and its motor competence.

Objective: In this study, we analyzed the intraoperative electrophysiological response obtained during vestibular schwannoma surgery. The ultrastructure was studied using electron microscopy.

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Background: An understanding of the normal topography during cerebellopontine angle surgery is necessary to obviate the anatomical distortions caused by tumors.

Objective: The aim of this study was to analyze the morphological features of the nervus intermedius (NI) and its related structures in the cerebellopontine angle (CPA).

Methods: Forty-three isolated human brainstems were examined to collect comprehensive morphometric and topographical data of the NI in its course from the brainstem to the ganglion geniculi, and discover its anatomical relationship with the other neurovascular structures in the CPA as well as within the meatus acusticus internus.

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The central myelin-peripheral myelin transitional zone, also referred to as the "Obersteiner-Redlich zone (ORZ)" or "glial/Schwann junction" of the nervus intermedius, is thought to play a role in the pathophysiology of nervus intermedius neuralgia (NIN). To evaluate the location and histological features of the ORZ of the nervus intermedius (NI), 10 NI specimens from five fresh cadavers were microscopically analyzed for structural differences between their central and peripheral myelin segments. The ORZ was analyzed under a light microscope, and the exact location of the ORZ was confirmed by immunohistochemical staining using an oligodendroglial antibody.

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