Publications by authors named "Julio Y Anaya-Covarrubias"
Scavenger receptors (SR) are not only pattern recognition receptors involved in the immune response against pathogens but are also important receptors exploited by different virus to enter host cells, and thus represent targets for antiviral therapy. The high mutation rates of viruses, as well as their small genomes are partly responsible for the high rates of virus resistance and effective treatments remain a challenge. Most currently approved formulations target viral-encoded factors.
View Article and Find Full Text PDFThe COVID-19 pandemic has widespread economic and social effects on Latin America (LA) and the Caribbean (CA). This region, which has a high prevalence of chronic diseases, has been one of the most affected during the pandemic. Multiple symptoms and comorbidities are related to distinct COVID-19 outcomes.
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- Hepatitis A virus (HAV) and hepatitis E virus (HEV) are significant contributors to global viral hepatitis, particularly affecting children in endemic regions.
- A study examined pediatric patients in South and West Mexico, revealing that all samples tested positive for HAV mono-infection, with higher prevalence during rainy seasons in the South.
- No HEV mono-infection was found, but co-infections with both viruses were common, highlighting different seasonal and geographical patterns of HAV and HEV infections across the regions.
Human immunodeficiency virus (HIV) predisposes for liver damage during coinfection with hepatitis E virus (HEV) and increases the replication of hepatitis C virus (HCV). HIV-hepatitis B virus (HBV) coinfections are common. In Mexico, hepatotropic viruses are major causative agents of liver disease.
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