An Experimental Murine Model to Study Lipoatrophia Semicircularis.

Lipoatrophia semicircularis is a benign pathology characterized by subcutaneous tissue atrophy that affects the skin and related structures. Its etiology remains unclear; however, in the recent few years, it has been proposed that electrostatic charges could be a potential factor. Based on this hypothesis, the aim of this work is to study the cause-effect relation between electrostatic energy and LS, providing insights into the molecular mechanisms.

Semicircular lipoatrophy: an electrostatic hypothesis.

Background: Semicircular lipoatrophy (SL) is a benign pathology characterized by subcutaneous adipose tissue atrophy.

Objective: To determine causes of SL.

Methods: We performed research on 42 cases of SL who had developed symptoms of lipoatrophy with a technical study of the building and clinical study of the affected patients.

Morphological and thermodynamic comparison of the lesions created by 4 open-irrigated catheters in 2 experimental models.

Introduction: New generation open-irrigated catheters aim to improve irrigation efficiency. This may change lesion patterns, challenging operators. Indeed, safety issues have recently arisen.