Observation of Ultra-High-Q Resonators in the Ultrasound via Bound States in the Continuum.

The confinement of waves in open systems represents a fundamental phenomenon extensively explored across various branches of wave physics. Recently, significant attention is directed toward bound states in the continuum (BIC), a class of modes that are trapped but do not decay in an otherwise unbounded continuum. Here, the theoretical investigation and experimental demonstration of the existence of quasi-bound states in the continuum (QBIC) for ultrasonic waves are achieved by leveraging an elastic Fabry-Pérot metasurface resonator.

Non-reciprocal and non-Newtonian mechanical metamaterials.

Non-Newtonian liquids are characterized by stress and velocity-dependent dynamical response. In elasticity, and in particular, in the field of phononics, reciprocity in the equations acts against obtaining a directional response for passive media. Active stimuli-responsive materials have been conceived to overcome it.

Behavioral signatures of face perception emerge in deep neural networks optimized for face recognition.

Human face recognition is highly accurate and exhibits a number of distinctive and well-documented behavioral "signatures" such as the use of a characteristic representational space, the disproportionate performance cost when stimuli are presented upside down, and the drop in accuracy for faces from races the participant is less familiar with. These and other phenomena have long been taken as evidence that face recognition is "special". But why does human face perception exhibit these properties in the first place? Here, we use deep convolutional neural networks (CNNs) to test the hypothesis that all of these signatures of human face perception result from optimization for the task of face recognition.

Zika virus infection induces expression of NRF2 and antioxidant systems in trophoblast cells.

The nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that plays a critical role in the xenobiotic and stress responses. During viral infection, NRF2 can modulate the host metabolism and innate immunity; however, the most common activity of NRF2 in viral diseases is controlling reactive oxygen species (ROS). The Zika virus (ZIKV) is involved in a vertical infection in pregnancy, with reported fetal health consequences.

Characteristics and factors associated with mortality due to rare diseases in Chile, 2002-2017.

Introduction: Rare diseases are characterized by their low prevalence, chronically debilitating and life-threatening nature. Objective: To determine the characteristics and factors associated with mortality due to rare diseases in Chile from 2002 to 2017. Materials and methods: We conducted an analytical cross-sectional study based on secondary mortality database from the Departamento de Estadística e Información en Salud (DEIS), Ministerio de Salud de Chile (Department of Statistics and Health Information, Chile Ministry of Health) from 2002 to 2017.

Brain-like functional specialization emerges spontaneously in deep neural networks.

The human brain contains multiple regions with distinct, often highly specialized functions, from recognizing faces to understanding language to thinking about what others are thinking. However, it remains unclear why the cortex exhibits this high degree of functional specialization in the first place. Here, we consider the case of face perception using artificial neural networks to test the hypothesis that functional segregation of face recognition in the brain reflects a computational optimization for the broader problem of visual recognition of faces and other visual categories.

Bariatric surgery on social media: A cross-sectional study.

Introduction: Bariatric Surgery (BS) represents a viable option for the treatment of obesity and its risks. Nevertheless, it is still being underused by the eligible patient population because of the general lack of information, false beliefs, and the stigmatization of obesity. Social media seems to be a solution for overcoming this problem.

Micro-Scale Auxetic Hierarchical Mechanical Metamaterials for Shape Morphing.

Shape morphing and the possibility of having control over mechanical properties via designed deformations have attracted a lot of attention in the materials community and led to a variety of applications with an emphasis on the space industry. However, current materials normally do not allow to have a full control over the deformation pattern and often fail to replicate such behavior at low scales which is essential in flexible electronics. Thus, in this paper, novel 2D and 3D microscopic hierarchical mechanical metamaterials using mutually-competing substructures within the system that are capable of exhibiting a broad range of the highly unusual auxetic behavior are proposed.

Clinical and Descriptive Study of Orofacial Clefts in Colombia: 2069 Patients From Operation Smile Foundation.

Objective: To describe the population of patients with cleft lip and/or palate (CL/P) in terms of cleft phenotypes, gender, age, ethnic group, family history, clinical presentation (syndromic vs nonsyndromic), some environmental and behavioral factors, and some clinical features.

Design: Descriptive retrospective study.

Setting: Patients attending the genetics counseling practice in Operation Smile Foundation, Bogotá, Colombia, for over 8 years.

De curandis hominum morbis: An 18th century medical prescription for measles and smallpox in the Nuevo Reino de Granada.

A collection of more than one hundred medical recipes from the late 18th century was donated by Presbyter Cipriano Rodríguez Santa María, institutional eponym of the collection at the Historical Archive “Octavio Arizmendi Posada” of the library of the Universidad de La Sabana in Colombia. These texts represent an important historical and medical legacy and they constitute an important basis for understanding the colonial and traditional therapeutics related to various diseases. In this article, we describe one of these recipes for the treatment of smallpox and measles as a contribution to the history of medicine in Colombia.

The Importance of investigating Mycobacterium bovis in clinical samples of human origin.

Introduction: Tuberculosis is an infectious disease that still represents a major public health problem worldwide. It is one of the main causes of mortality in people with HIV. Objective: To identify the presence of M.

[Los niveles de mediadores prorresolutivos no corresponden con los de mediadores inflamatorios en enfermedades isquémicas coronarias].

Background: Inflammation can be grouped into three phases: proinflammatory, anti-inflammatory, and resolution. The latter, mainly attributed to lipid mediators, is the most recently described, and has been studied little in coronary ischemic diseases.

Objective: To evaluate 1) if acute coronary syndromes (ACS) manifest different circulating levels of resolution mediators compared with stable angina (SA); 2) if their concentrations are related to those of pro and anti-inflammatory mediators; and 3) if such concentrations are associated with the severity of the disease and the damage produced.

Rare diseases mortality in Colombia, 2008-2013.

Introduction: Rare diseases are characterized by their low prevalence, often of genetic origin, degenerative and life threatening. Objective: To describe mortality by orphan diseases and to analyze its trends in Colombia from 2008 to 2013. Materials and methods: We conducted a descriptive study to analyze mortality rate trends from the death certificates between 2008 and 2013.

Evaluating the Feasibility of Incorporating In-Person Interpreters on Family-Centered Rounds: A QI Initiative.

Objectives: No best practice has been defined for incorporating in-person interpreters into family-centered rounds (FCRs) for patients with limited English proficiency (LEP). We hypothesized that addressing barriers to scheduling in-person interpreters would make FCR encounters more likely, and thus ensure more equitable care for LEP patients.

Methods: A quality improvement initiative was conducted from October 2014 to March 2016 to arrange in-person interpreters for LEP patients during FCRs on the inpatient pediatric service of a large, urban, tertiary care center in Boston.

Dosimetry of the left anterior descending coronary artery in left breast cancer patients treated with postoperative external radiotherapy.

Aim: To evaluate the dose distribution to the left anterior descending (LAD) coronary artery in patients treated with postoperative three-dimensional conformal radiotherapy (3DCRT).

Background: Postoperative radiotherapy may increase the risk of heart disease, particularly in patients with left-sided breast cancer. Clinical data on doses to the LAD are limited.

A road map for leptospirosis research and health policies based on country needs in Latin America.

This report summarizes the presentations, discussions and the recommendations coming from the Oswaldo Cruz Institute/FIOCRUZ International Workshop for Leptospirosis Research Based on Country Needs and the 5th Global Leptospirosis Environmental Action Network meeting, which was held in the city of Rio de Janeiro, Brazil, 10-12 November 2015. The event focused on health policy and worked to develop a road map as a consensus document to help guide decision-making by policymakers, funding bodies, and health care professionals. The direction that leptospirosis research should take in the coming years was emphasized, taking into account the needs of countries of Latin America, as well as experiences from other world regions, as provided by international experts.

[Factors associated to mortality by non-communicable diseases in Colombia, 2008-2012].

Introduction: Non-communicable diseases are the leading cause of premature mortality and disability in the world.

Objective: To describe the trend pattern and to explore which risk factors were associated with mortality rates in Colombia from 2008 to 2012.

Materials And Methods: A descriptive study was conducted to analyze mortality rate trends from the official vital statistics (death certificates) from 2008 to 2012.

Deleterious coding variants in multi-case families with non-syndromic cleft lip and/or palate phenotypes.

Nonsyndromic Cleft Lip and/or Palate (NSCLP) is regarded as a multifactorial condition in which clefting is an isolated phenotype, distinguished from the largely monogenic, syndromic forms which include clefts among a spectrum of phenotypes. Nonsyndromic clefting has been shown to arise through complex interactions between genetic and environmental factors. However, there is increasing evidence that the broad NSCLP classification may include a proportion of cases showing familial patterns of inheritance and contain highly penetrant deleterious variation in specific genes.

Enhanced thermoelectric transport in modulation-doped GaN/AlGaN core/shell nanowires.

The thermoelectric properties of unintentionally n-doped core GaN/AlGaN core/shell N-face nanowires are reported. We found that the temperature dependence of the electrical conductivity is consistent with thermally activated carriers with two distinctive donor energies. The Seebeck coefficient of GaN/AlGaN nanowires is more than twice as large as that for the GaN nanowires alone.

Simultaneous Thermoelectric and Optoelectronic Characterization of Individual Nanowires.

Semiconducting nanowires have been explored for a number of applications in optoelectronics such as photodetectors and solar cells. Currently, there is ample interest in identifying the mechanisms that lead to photoresponse in nanowires in order to improve and optimize performance. However, distinguishing among the different mechanisms, including photovoltaic, photothermoelectric, photoemission, bolometric, and photoconductive, is often difficult using purely optoelectronic measurements.

Species in Wolbachia? Proposal for the designation of 'Candidatus Wolbachia bourtzisii', 'Candidatus Wolbachia onchocercicola', 'Candidatus Wolbachia blaxteri', 'Candidatus Wolbachia brugii', 'Candidatus Wolbachia taylori', 'Candidatus Wolbachia collembolicola' and 'Candidatus Wolbachia multihospitum' for the different species within Wolbachia supergroups.

Wolbachia are highly extended bacterial endosymbionts that infect arthropods and filarial nematodes and produce contrasting phenotypes on their hosts. Wolbachia taxonomy has been understudied. Currently, Wolbachia strains are classified into phylogenetic supergroups.

Clinical, endoscopic and manometric features of the primary motor disorders of the esophagus.

Background: Significant incidence, diagnostic difficulties, clinical relevance and therapeutic efficacy associated with the small number of publications on the primary esophageal motor disorders, motivated the present study.

Aim: To determine the manometric prevalence of these disorders and correlate them to the endoscopic and clinical findings.

Methods: A retrospective study of 2614 patients, being 1529 (58.