Flindissone, a Limonoid Isolated from , Is an LXR Agonist.

In this study, the ability of six limonoids from (Meliaceae) to activate the liver X receptor (LXR) was assessed. One of these limonoids, flindissone, was shown to activate LXR by reporter-gene assays. Flindissone is a ring-intact limonoid, structurally similar to sterol-like LXR ligands.