Publications by authors named "Julio Gutierrez Hernandez"
Nucleic Acids Res
June 2019
Article Synopsis
- Alternative splicing is influenced by accessory proteins, and while most recognize the RNA polymerase II tail, SFPQ does not, yet it is critical for RNA processing in mammals.
- The study highlights Dido3, a product of the Dido gene, revealing its role in alternative splicing as it interacts with SFPQ, showing how Dido3 mutations affect SFPQ binding and exon skipping.
- The findings suggest Dido3 acts as an adaptor for SFPQ in RNA splicing, allowing mammals to regulate exon usage efficiently by distributing splicing factor recruitment across different pathways.
