Publications by authors named "Juliette Laure Ndzie Ondigui"
Article Synopsis
- Hepatitis B virus (HBV) and hepatitis delta virus (HDV) co-infection is severe and can be transmitted from mother to child, with significant rates found in pregnant women in Cameroon.
- A study involving 1992 pregnant women revealed a 6.7% prevalence of HBsAg, with 32.3% of HBsAg-positive women also being anti-HDV antibody-positive and almost half showing detectable HDV RNA levels.
- Risk factors linked to HDV presence included multiple pregnancies and body modifications like tattoos, highlighting the need for awareness and preventive measures against maternal transmission of HDV.
Toward the elimination of hepatitis B: networking to promote the prevention of vertical transmission of hepatitis B virus through population-based interventions and multidisciplinary groups in Africa.
Front Public Health
April 2024
The WHO African Region had 81 million people with chronic hepatitis B in 2019, which remains a silent killer. Hepatitis B virus (HBV), hepatitis delta virus (HDV), and HIV can be transmitted from the mother to child. If the HBV infection is acquired at infancy, it may lead to chronic hepatitis B in 90% of the cases.
View Article and Find Full Text PDFDialysis is a replacement therapy for patients with End-Stage Renal Disease (ESRD). Patients on dialysis are at high risk of acquiring hepatitis C virus (HCV), which has become a leading cause of morbidity and mortality in this population. There is a wide range of prevalence of HCV in dialysis populations around the world.
View Article and Find Full Text PDFSystematic review and meta-analysis of seroprevalence of human immunodeficiency virus serological markers among pregnant women in Africa, 1984-2020.
World J Crit Care Med
December 2023
Article Synopsis
- HIV is a significant public health issue in Africa, particularly affecting pregnant women, which impacts both maternal and child health.
- The study reviewed 248 articles to determine the overall HIV seroprevalence among pregnant women in Africa, finding a rate of 9.3%, with notable regional differences.
- The highest seroprevalence was in Southern Africa (29.4%), while Northern Africa had the lowest (0.7%), indicating considerable variation in HIV rates across the continent.
Astroviruses (AstVs) are a major cause of gastroenteritis, especially in children. They can be transmitted through various pathways, including environmental contamination via water matrices. This study aimed to investigate the prevalence of AstV in different types of water, such as untreated and treated wastewater, surface water (e.
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- Bacterial vaginosis (BV) significantly impacts pregnant women, leading to serious maternal and fetal complications, including potential fatal outcomes.
- A comprehensive meta-analysis of 26 relevant studies revealed high rates of preterm birth (17.9%), low birth weight (14.2%), and maternal issues like premature rupture of membranes (13.2%) linked to BV.
- The study found strong associations between BV and adverse outcomes, including preterm birth (OR 1.76) and miscarriage (OR 2.34), highlighting the necessity for better awareness and management of BV in pregnant women.
Article Synopsis
- The study aimed to estimate the prevalence of metabolic syndrome (MS) in African populations, noting its global health impact and prior lack of specific prevalence data for Africa.
- It conducted a systematic review of 297 studies across 29 African countries, analyzing the prevalence rates using various diagnostic methods, which revealed a pooled prevalence of 32.4% for MS overall in Africa.
- The results indicated higher prevalence in adults (33.1%) than children (13.3%), with MS being more common in females (36.9%) versus males (26.7%), and particularly prevalent among patients with Type 2 diabetes (66.9%).
Hepatitis A is a common form of viral hepatitis. It is usually transmitted through the ingestion of contaminated food and water. This systematic review was carried out to summarise the overall prevalence of Hepatitis A virus (HAV) in different water matrices: untreated and treated wastewater, surface water, groundwater, drinking water, and others (e.
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- Occult hepatitis B (OBI) and C (OCI) infections are serious health issues in Africa, leading to liver complications like cirrhosis and cancer, and pose risks for transmission.
- A systematic review and meta-analysis examined OBI and OCI prevalence across Africa, utilizing data from multiple published studies.
- The findings indicated that OBI has a prevalence of about 14.8%, while OCI is around 10.7%, with higher rates observed in specific patient populations such as those with liver disorders and malignancies.
This study aimed to assess the global prevalence of occult hepatitis B in blood donors. We searched PubMed, Web of Science, Global Index Medicus, and Excerpta Medica Database. Study selection and data extraction were performed by at least two independent investigators.
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- Yellow fever (YF) has seen a resurgence over the past two decades, leading to outbreaks in endemic areas and new regions, which poses significant public health challenges.
- This systematic review analyzed data on the case fatality rate (31.1% in humans) and the prevalence of the yellow fever virus (YFV) in humans (9.4%), mosquitoes, and non-human primates in sub-Saharan Africa, based on 55 studies.
- The findings emphasize the ongoing virus transmission and highlight the urgent need for strategies like the WHO's Eliminate Yellow Fever Epidemics initiative to prevent future outbreaks in the region.
Background: Occult hepatitis C infection (OCI) is characterized by the presence of hepatitis C virus (HCV) RNA in the liver, peripheral blood mononuclear cells (PBMC) and/or ultracentrifuged serum in the absence of detectable HCV-RNA in serum. OCI has been described in several categories of populations including hemodialysis patients, patients with a sustained virological response, immunocompromised individuals, patients with abnormal hepatic function, and apparently healthy subjects.
Aim: To highlight the global prevalence of OCI.
Epidemiology of hepatitis B virus and/or hepatitis C virus infections among people living with human immunodeficiency virus in Africa: A systematic review and meta-analysis.
PLoS One
June 2022
Article Synopsis
- In Africa, HIV coinfection with hepatitis B (HBV) and hepatitis C (HCV) is a significant public health issue, yet data on its epidemiology and case fatality rates are limited.
- A systematic review of 4388 articles identified 314 studies, revealing a 4.4% case fatality rate for HBV among people living with HIV (PLHIV) and various prevalence rates for HBV (10.5%), HCV (5.4%), and their coinfection (0.7%).
- The findings highlight the need for targeted public health efforts to address the complex interplay of these infections in Africa, given the observed variability and challenges in data reporting.