Publications by authors named "Juliette C van Hattum"

Aims: To quantitatively analyse exercise-induced cardiac remodeling (EICR) data in female athletes.

Methods: This scoping review included from the databases Medline, Embase, and Google Scholar, peer-reviewed original English-language articles on female athlete-populations aged ≥18 years containing data on electrocardiography (ECG), echocardiography or cardiac magnetic resonance (CMR), and excluded athletes with cardiovascular conditions. From the extracted ECG data, we calculated prevalence percentages, and from the imaging data we compared the results with the upper reference limits of the general female population (URL).

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Objective: Longitudinal consequences and potential interactions of COVID-19 and elite-level sports and exercise are unclear. Therefore, we determined the long-term detrimental cardiac effects of the interaction between SARS-CoV-2 infection and the highest level of sports and exercise.

Methods: This prospective controlled study included elite athletes from the Evaluation of Lifetime participation in Intensive Top-level sports and Exercise cohort.

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The recognition of myocarditis as a rare side effect of SARS-CoV-2 mRNA vaccination has sparked a global debate on vaccine safety, especially in the realm of sports. The main proposed mechanisms in the pathogenesis of COVID-19 mRNA vaccination-associated myocarditis (C-VAM) are based on the activation of the innate- and adaptive immune system against a susceptible immune-genetic background, including the recognition of mRNA as an antigen by the immune system, molecular mimicry between SARS-CoV-2 spike glycoprotein and cardiac tissue antigens and inflammatory sex-hormone signalling. The relatively younger age of the athlete population hypothetically constellates an increased risk of C-VAM.

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Background And Aim: The efficacy of pre-COVID-19 and post-COVID-19 infection 12-lead ECGs for identifying athletes with myopericarditis has never been reported. We aimed to assess the prevalence and significance of de-novo ECG changes following COVID-19 infection.

Methods: In this multicentre observational study, between March 2020 and May 2022, we evaluated consecutive athletes with COVID-19 infection.

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Introduction: The cardiovascular benefits of physical exercise are well-known. However, vigorous exercise has also been associated with adverse cardiac effects. To improve our understanding of cardiovascular adaptation to exercise versus maladaptation and pathology, the limits of adaptation should be firmly established using state-of-the-art diagnostic modalities.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of a structured sports cardiology multidisciplinary team (MDT) in managing athletes' cardiac health and practices.
  • Over 115 athletes received reviews from an expert panel, resulting in improved diagnosis accuracy, reduced cardiac pathology classifications, and tailored sports guidance.
  • The findings indicate that the MDT approach leads to better outcomes in terms of definitive diagnoses, increased adherence to advice, and fewer restrictions on athletic participation.
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Background: COVID-19 has been associated with myocardial abnormalities on cardiac magnetic resonance imaging (CMR). We report a case of COVID-19 myocarditis in an elite athlete.

Case Summary: A male, 21-year-old elite football player had tested positive for SARS-CoV-2 on a polymerase-chain-reaction test and was referred for cardiac evaluation after experiencing palpitations after returning to sports (RTS).

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Article Synopsis
  • Genetic variants linked to cardiomyopathies (CMPs) are common and can lead to sudden cardiac death, especially in young athletes, prompting concerns about participation in competitive sports.
  • Research suggests that these genetic variants might initially enhance physical performance in young individuals while potentially damaging heart function later.
  • A review of a limited number of studies found that individuals with CMP-related genetic variants demonstrated superior abilities in running speed, endurance, and muscle force compared to those without such variants, implying a potential role in athlete selection.
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Objectives: Quantification of pericardial/myocardial involvement and risks of sudden cardiac arrest/sudden cardiac death (SCA/SCD) after SARS-CoV-2 infection in athletes who return to sports.

Design: Systematic review on post-SARS-CoV-2 infection pericardial/myocardial manifestations in athletes.

Data Sources: Combinations of key terms in Medline, Embase and Scopus (through 2 June 2021).

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Background: Interventional cardiologists are increasingly exposed to radiation-induced diseases like cataract and the stochastic risk of left-sided brain tumors. The RADPAD is a sterile, disposable, lead-free shield placed on the patient with the aim to minimize operator-received scatter radiation. The objective of the trial was to examine the RADPAD's efficacy in a real-world situation.

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