Functional Characterization of an Interferon Gamma Receptor-Like Protein on Entamoeba histolytica.

is an anaerobic parasitic protozoan and the causative agent of amoebiasis. expresses proteins that are structurally homologous to human proteins and uses them as virulence factors. We have previously shown that binds exogenous interferon gamma (IFN-γ) on its surface, and in this study, we explored whether exogenous IFN-γ could modulate parasite virulence.

Curcumin Provides Hepatoprotection against Amoebic Liver Abscess Induced by in Hamster: Involvement of Nrf2/HO-1 and NF-B/IL-1 Signaling Pathways.

Amoebic liver abscess (ALA) is the most common extraintestinal amoebiasis caused by (). However, despite current knowledge and scientific advances about this infection, there are no effective treatments to prevent it. Herein, the antiamoebic capacity of curcumin in a hamster model was evaluated.

Adrenergic regulation during acute hepatic infection with Entamoeba histolytica in the hamster: involvement of oxidative stress, Nrf2 and NF-KappaB.

Oxidative stress and transcriptional pathways of nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor kappa-B (NF-κB) are critically involved in the etiopathology of amebic liver abscess (ALA). In this work, we studied the relationship between the adrenergic nervous system and ALA in the hamster. ALA was visible at 12 h of infection.