Publications by authors named "Julieta Conci"
Article Synopsis
- Interferon response suppression in respiratory syncytial virus (RSV) is facilitated by nonstructural proteins NS1 and NS2, which form high-order complexes with cellular partners.
- Proline residues P81 and P67 are crucial for the conformational changes that enable NS1 oligomerization, with P81 involved in stabilizing the structure and P67 influencing aggregation tendencies.
- Despite their spatial distance from the C-terminal helix, both proline mutations affect the stability of oligomerization and aggregation processes, highlighting a significant connection between structural dynamics and the functionality of NS1 in multiprotein complexes.
