Comparing dosing of basal insulin analogues detemir and glargine: is it really unit-per-unit and dose-per-dose?

Objective: To review the available evidence regarding dosing conversion between glargine and detemir in an effort to assist clinicians in performing dosing conversion.

Data Sources: A MEDLINE literature search was performed using the search terms glargine and detemir for articles published through August 2013.

Study Selection And Data Extraction: All English-language clinical trials were reviewed for inclusion of dosing and/or pharmacokinetic data.

Evaluation of patient satisfaction with diabetes management provided by clinical pharmacists in the patient-centered medical home.

Study Objective: The patient-centered medical home (PCMH) model is a multidisciplinary, team-based approach to healthcare that focuses on actively involving the patient in clinical decision making. Multiple studies have demonstrated improved clinical outcomes from utilizing clinical pharmacists in the primary care setting, particularly in management of diabetes. No study has evaluated patient satisfaction with pharmacist in the PCMH model.

Annual influenza vaccination: offering protection beyond infection.

Cardiovascular disease (CVD), the leading cause of death in the world, is largely preventable. An increasing amount of evidence suggests that annual vaccination with inactivated influenza vaccine reduces morbidity and mortality associated with CVD; however, immunization rates in patients with CVD fall consistently below the goals established by Healthy People 2020. This review outlines the importance of vaccination and summarizes the available literature on the role of seasonal influenza vaccination and the incidence of coronary artery disease and stroke.