Acute and sub acute toxicity of an effective Siddha herbo mineral formulation used in the treatment of rheumatoid arthritis in wistar albino rat model.

Objectives: (AGKV) is a herbo mineral Siddha formulation which has Sulphur, and as major ingredients and it is indicated for 80 types of diseases. is one among the diseases and it's clinical symptoms are correlated with Rheumatoid arthritis (RA). Since AGKV is a promising drug for RA, the safety of this drug has been validated by performing the acute and 28 days repeated oral dose toxicity study following the OECD guidelines 423 and 407.

Quantification of anacardic acid, the toxic component in raw and purified samples of L. by Siddha purification processes.

Objectives: The knowledge of purification process is unique since it deals with various physical and chemical changes in the inherent toxic properties during the process and it renders a strong support in the art of medicine preparation in Siddha system of medicine. L. is listed under Schedule e (1) drugs and purification is mandatory before its administration in medicine preparation.