Publications by authors named "Julien Roquain"
Br J Haematol
November 2010
Article Synopsis
- Chronic myelomonocytic leukaemia (CMML) is a complex blood cancer with both myelodysplastic and myeloproliferative features, but its molecular biology isn't fully understood.
- A study examined 53 CMML samples, identifying mutations in specific genes, particularly ASXL1, which were more prevalent in the myeloproliferative form (MP-CMML).
- Mutations in ASXL1 were linked to a worse prognosis and a higher likelihood of progressing to acute leukaemia, as all patients who progressed had this mutation while none without it did.
