Synthesis and antibacterial properties under blue LED light of conjugates between the siderophore desferrioxamine B (DFOB) and an Iridium(III) complex.

The decline of antibiotics efficacy worldwide has recently reached a critical point urging for the development of new strategies to regain upper hand on multidrug resistant bacterial strains. In this context, the raise of photodynamic therapy (PDT), initially based on organic photosensitizers (PS) and more recently on organometallic PS, offers promising perspectives. Many PS exert their biological effects through the generation of reactive oxygen species (ROS) able to freely diffuse into and to kill surrounding bacteria.

Low-frequency electric muscle stimulation combined with physical therapy after total hip arthroplasty for hip osteoarthritis in elderly patients: a randomized controlled trial.

Objective: To assess the effects of low-frequency electric muscle stimulation associated with usual physiotherapy on functional outcome after total hip arthroplasty (THA) for hip osteoarthritis (OA) in elderly subjects.

Design: Randomized controlled trial; pre- and posttreatment measurements.

Setting: Hospital rehabilitation department.

Changes in social exploration of a lipopolysaccharides-treated conspecific in mice: role of environmental cues.

Despite the many advantages offered by sociality in animals, one of its main drawbacks is the increased propensity to be exposed to parasites and pathogens. In infection (bacteria and viruses), one of the common symptoms used to describe an animal experiencing an acute inflammation is a "social disinterest". According to the literature, this reduction in social behaviors would be an adaptive feature preventing further contamination.

Immunity and emotions: lipopolysaccharide increases defensive behaviours and potentiates despair in mice.

Many studies have pointed out the relationships between immunity and depression, supporting a neuroimmune hypothesis of depressive disorders. However, despite the growing interest for such a hypothesis and the amount of clinical and experimental data available, the precise nature of this relationship between immunity and depression remains unclear. The present study aimed to investigate further the link between depression and immunity in mice using the modified version of the forced-swimming test.