Exploring the solid-state phases and thermodynamics of calcium l-lactate.

Calcium l-lactate, an organic salt derived from l-lactic acid, is used in many fields such as food, pharmaceutical or cosmetic industry. To this date, its solid-state thermodynamics are still poorly understood: a pentahydrate crystalline and anhydrate amorphous forms were already characterized, and potential other hydrates mentioned in literature. For the development of a robust crystallization process or down-line handling of this compound, it is important to know and understand the relationship between the different solid forms to prevent uncontrolled crystallization or solid-solid transformation during storage.