Interferometric Biosensor for High Sensitive Label-Free Recording of HiPS Cardiomyocytes Contraction .

Heart disease remains a leading cause of global mortality, underscoring the need for advanced technologies to study cardiovascular diseases and develop effective treatments. We introduce an innovative interferometric biosensor for high-sensitivity and label-free recording of human induced pluripotent stem cell (hiPSC) cardiomyocyte contraction . Using an optical cavity, our device captures interference patterns caused by the contraction-induced displacement of a thin flexible membrane.